about Fentanyl class, uses, side effects contraindications
Fentanyl
Short Description
Fentanyl belongs to the narcotic or opiate family of pain relievers and is available in several ways, and it works by changing the way the brain and nervous system respond to pain.
Oral fentanyl is used to treat sudden attacks of pain in cancer patients who regularly take opioid pain relievers and no longer have an effect as their bodies adapt to them.
Also, transdermal patch therapy aims to relieve moderate to severe chronic pain, which does not respond to other opioid pain relievers.
But unlike the oral or dermal fentanyl methods, the injection is intended for short-term pain relief, such as: surgery pain, in addition to its use in general anesthesia.
Long-term use of fentanyl, as is the case with other opioid analgesics, can lead to dependence and addiction of the patient to the analgesic. However, short-term consumption will not cause dependence on treatment, and it is possible to stop using it without difficulties.
Trade Name & Company Name
effect of Fentanyl in Pregnancy, Fetal Health
and Breast feeding
Pregnancy
. Fentanyl is a short-acting opiate with considerable risk of abuse. It is often combined during labor with local anesthetics to minimize motor blockade for epidural anesthesia. Fentanyl may be used safely in women with severe preeclampsia. It is a useful adjunct to a paracervical block for suction curettage. The chance 393 of a successful external version is increased by its use with spinal blockade. Its addition to 2.2ml of 0.5% hyperbaric bupivacaine with 0.2ml of morphine 0.2mg intrathecally reduces the incidence and severity of intraoperative and postoperative shivering after spinal anesthesia for cesarean delivery without increasing other Side effects include respiratory depression or arrest, dependency, laryngospasm, bronchospasm, arrhythmias, ileus, cardiac arrest, N/V, weakness, dry mouth, confusion, sweating, euphoria, itching, hypotension, and bradycardia. Fetal Health
There are no adequate reports or well-controlled studies in human fetuses. Fentanyl rapidly crosses the human placenta, achieving an F:M ratio approximating unity. It crosses the fetal blood-brain barrier and has been used for fetal analgesia where a reduction in endorphin levels is demonstrated. Rodent studies are generally reassuring, revealing no evidence of teratogenicity or IUGR despite the use of doses higher than those used clinically. It is embryotoxic in rodents. Breastfeeding There are no adequate reports or well-controlled studies in nursing women. Fentanyl enters human breast milk, but is not likely to pose a risk to the neonate of an alert,
the follwing drugs will increse Fentanyl by inhepiting cyp450
amiodarone ; aprepitant ; atomoxetine ; boceprevir ; ceritinib ; chloramphenicol ; cimetidine ; ciprofloxacin ; clarithromycin ; crizotinib ; delaviridine ; diethyl-dithiocarbamate ; diltiazem ; entrectinib ; erythromycin ; esomeprazole ; fluconazole ; fluvoxamine ; gestodene ; grapefruit juice ; idelalisib ; imatinib ; indinavir ; itraconazole ; ivacaftor ; ketoconazole ; lesinurad ; letermovir ; mibefradil ; mifepristone ; nefazodone ; nelfinavir ; netupitant/palonosetron ; norfloxacin ; norfluoxetine ; omeprazole ; pantoprazole ; perampanel ; quercetin ; regorafenib ; ribociclib ; ritonavir ; rucaparib ; saquinavir ; simeprevir ; starfruit ; telaprevir ; telithromycin ; ticagrelor ; tucatinib ; verapamil ; voriconazole ;
the follwing drugs will decrease Fentanyl by inhancing cyp450
barbiturates ; brigatinib ; carbamazepine ; clobazam ; dabrafenib ; efavirenz ; elagolix ; enzalutamide ; eslicarbazepine ; glucocorticoids ; letermovir ; lorlatinib ; modafinil ; nevirapine ; oxcarbazepine ; perampanel ; phenobarbital ; phenytoin ; pioglitazone ; rifabutin ; rifampin ; St. John's Wort ; telotristat ; troglitazone ; vemurafenib ;
Catogary
Narcotic analgesicsAnalgesics (painkillers) are drugs that relieve pain. Since pain is not a disease but a symptom, long-term relief depends on treatment of the underlying cause. ...
trad drugs based on Fentanyl
| Gen name | Trade name | Catagory name |
| fentanyl | Abstral | Narcotic analgesics |
| fentanyl | Actiq | Narcotic analgesics |
| fentanyl | Duragesic | Narcotic analgesics |
| fentanyl | Fentanyl Transdermal System | Narcotic analgesics |
| fentanyl | Fentora | Narcotic analgesics |
| fentanyl | Ionsys | Narcotic analgesics |
| fentanyl | Lazanda | Narcotic analgesics |
| fentanyl | Onsolis | Narcotic analgesics |
| fentanyl | Sublimaze | Narcotic analgesics |
| fentanyl | Subsys | Narcotic analgesics |
| Fentanyl | DUROGESIC 12MCG-H TRASDERMAL PATCHES | |
| Fentanyl | DUROGESIC TTS 100 Ug-HOUR | |
| Fentanyl | DUROGESIC TTS 25 Ug-HOUR | |
| Fentanyl | DUROGESIC TTS 50 Ug-HOUR | |
| Fentanyl | DUROGESIC TTS 75 Ug-HOUR | |
| Fentanyl | FENTANYL CITRATE 50MCG-ML VIAL | |
| Fentanyl | FENTANYL-JANSSEN 0.05MG-ML AMPOULES | |
other drugs from same cataogory