The following drugs will decrease nevirapine effect

#	enzyme	inducers
0	3A457	barbiturates
1	3A457	brigatinib
2	3A457	carbamazepine
3	3A457	clobazam
4	3A457	dabrafenib
5	3A457	efavirenz
6	3A457	elagolix
7	3A457	enzalutamide
8	3A457	eslicarbazepine
9	2B6	artemisinin
10	3A457	glucocorticoids
11	3A457	letermovir
12	3A457	lorlatinib
13	3A457	modafinil
14	3A457	nevirapine
15	3A457	oxcarbazepine
16	3A457	perampanel
17	3A457	phenobarbital
18	3A457	phenytoin
19	3A457	pioglitazone
20	3A457	rifabutin
21	3A457	rifampin
22	3A457	St. John's Wort
23	3A457	telotristat
24	3A457	troglitazone
25	3A457	vemurafenib
26	2B6	carbamazepine
27	2B6	dabrafenib
28	2B6	efavirenz
29	2B6	letermovir
30	2B6	nevirapine
31	2B6	perampanel
32	2B6	phenobarbital
33	2B6	phenytoin
34	2B6	rifampin
35	2B6	roflumilast

the follwing drugs will Increase nevirapine effect

#	enzyme	Inhibitors	level
0	3A457	amiodarone	under review
1	3A457	aprepitant	Moderate inhibitor
2	3A457	atomoxetine
3	3A457	boceprevir	under review
4	3A457	ceritinib	Strong inhibitor
5	3A457	chloramphenicol	In-Vitro Only
6	3A457	cimetidine
7	3A457	ciprofloxacin	under review
8	3A457	clarithromycin	Strong inhibitor
9	2B6	clopidogrel	Weak inhibitor
10	3A457	crizotinib	Moderate inhibitor
11	3A457	delaviridine	under review
12	3A457	diethyl-dithiocarbamate
13	3A457	diltiazem	Moderate inhibitor
14	3A457	entrectinib
15	3A457	erythromycin	Moderate inhibitor
16	3A457	esomeprazole
17	3A457	fluconazole	Moderate inhibitor
18	3A457	fluvoxamine	under review
19	3A457	gestodene	under review
20	3A457	grapefruit juice	Moderate inhibitor
21	3A457	idelalisib	Strong inhibitor
22	3A457	imatinib	under review
23	3A457	indinavir	Strong inhibitor
24	3A457	itraconazole	Strong inhibitor
25	3A457	ivacaftor
26	3A457	ketoconazole	Strong inhibitor
27	3A457	lesinurad
28	3A457	letermovir
29	3A457	mibefradil	Strong inhibitor
30	3A457	mifepristone	under review
31	3A457	nefazodone	Strong inhibitor
32	3A457	nelfinavir	Strong inhibitor
33	3A457	netupitant/palonosetron	Moderate inhibitor
34	3A457	norfloxacin	under review
35	3A457	norfluoxetine	under review
36	3A457	omeprazole	Weak inhibitor
37	3A457	pantoprazole
38	3A457	perampanel
39	3A457	quercetin
40	3A457	regorafenib	under review
41	3A457	ribociclib	Strong inhibitor
42	3A457	ritonavir	Strong inhibitor
43	3A457	rucaparib
44	3A457	saquinavir	Strong inhibitor
45	3A457	simeprevir
46	3A457	starfruit	under review
47	3A457	telaprevir	under review
48	3A457	telithromycin	Strong inhibitor
49	2B6	thiotepa	Weak inhibitor
50	3A457	ticagrelor
51	2B6	ticlopidine	Strong inhibitor
52	3A457	tucatinib	Strong inhibitor
53	3A457	verapamil	Moderate inhibitor
54	2B6	voriconazole	Moderate inhibitor
55	3A457	voriconazole	Strong inhibitor

The following drugs will decreased effect by nevirapine effect

#	enzyme	drug
1	3A457	abemaciclib
2	3A457	abiraterone
3	3A457	acalabrutinib
4	3A457	alectinib
5	3A457	alfentanil
6	3A457	alprazolam
7	2C9	amitriptyline
8	3A457	amitriptyline
9	3A457	amlodipine
10	3A457	apixaban
11	3A457	aprepitant
12	3A457	aripiprazole
13	2B6	artemisinin
14	3A457	astemizole
15	3A457	atorvastatin
16	3A457	avanafil
17	3A457	axitinib
18	2C9	azilsartan
19	3A457	boceprevir
20	3A457	bosutinib
21	3A457	brexpiprazole
22	3A457	brigatinib
23	2B6	bupropion
24	3A457	buspirone
25	3A457	cafergot
26	3A457	caffeine
27	2C9	capecitabine
28	3A457	carbamazepine
29	3A457	cariprazine
30	2C9	celecoxib
31	3A457	ceritinib
32	3A457	cerivastatin
33	3A457	chlorpheniramine
34	3A457	cilostazol
35	3A457	cisapride
36	3A457	citalopram
37	3A457	clarithromycin
38	2B6	clobazam
39	3A457	clobazam
40	2C9	clopidogrel
41	3A457	clopidogrel
42	3A457	cobimetinib
43	3A457	cocaine
44	3A457	codeine
45	3A457	colchicine
46	3A457	copanlisib
47	3A457	crizotinib
48	2B6	cyclophosphamide
49	3A457	cyclosporine
50	3A457	dabrafenib
51	3A457	daclatasvir
52	3A457	dapsone
53	3A457	deflazacort
54	3A457	dexamethasone
55	3A457	dextromethorphan
56	3A457	diazepam
57	2C9	diclofenac
58	3A457	diltiazem
59	3A457	docetaxel
60	3A457	dolutegravir
61	3A457	domperidone
62	2C9	doxepin
63	3A457	doxepin
64	2B6	efavirenz
65	3A457	elagolix
66	3A457	elbasvir/grazoprevir
67	3A457	eliglustat
68	3A457	enzalutamide
69	3A457	eplerenone
70	3A457	erythromycin2
71	3A457	escitalopram
72	3A457	esomeprazole
73	3A457	estradiol
74	3A457	felodipine
75	3A457	fentanyl
76	3A457	finasteride
77	3A457	flibanserin
78	2C9	fluoxetine
79	2C9	fluvastatin
80	3A457	gleevec
81	2C9	glibenclamide
82	2C9	glimepiride
83	2C9	glipizide
84	2C9	glyburide
85	3A457	haloperidol
86	3A457	hydrocortisone
87	3A457	ibrutinib
88	2C9	ibuprofen
89	3A457	idelalisib
90	2B6	ifosphamide
91	3A457	indacaterol
92	3A457	indinavir
93	2C9	irbesartan
94	3A457	irinotecan
95	3A457	isavuconazonium
96	3A457	ivabradine
97	3A457	ivacaftor
98	2B6	ketamine
99	3A457	LAAM
100	3A457	lansoprazole
101	3A457	lenvatinib
102	3A457	lercanidipine
103	2C9	lesinurad
104	3A457	lidocaine
105	3A457	linagliptin
106	2C9	lornoxicam
107	2C9	losartan
108	3A457	lovastatin
109	3A457	macitentan
110	3A457	mavacamten
111	2C9	meloxicam
112	2B6	meperidine
113	2B6	methadone
114	3A457	methadone
115	3A457	midazolam
116	3A457	naldemedine
117	3A457	naloxegol
118	2C9	nateglinide
119	3A457	nateglinide
120	3A457	nelfinavir
121	3A457	neratinib
122	3A457	netupitant/palonosetron
123	2B6	nevirapine
124	3A457	nevirapine
125	3A457	nifedipine
126	3A457	nirmatrelvir
127	3A457	nisoldipine
128	3A457	nitrendipine
129	3A457	olaparib
130	2C9	olodaterol
131	3A457	omeprazole
132	3A457	ondansetron
133	3A457	osimertinib
134	2C9	ospemifene
135	3A457	ospemifene
136	3A457	palbociclib
137	3A457	panobinostat
138	3A457	pantoprazole
139	3A457	perampanel
140	2C9	phenytoin
141	3A457	pimavanserin
142	3A457	pimozide
143	2C9	piroxicam
144	3A457	pomalidomide
145	3A457	ponatinib
146	3A457	progesterone
147	2B6	propafol
148	3A457	propranolol
149	3A457	quetiapine
150	3A457	quinidine
151	3A457	quinine
152	3A457	regorafenib
153	3A457	ribociclib
154	3A457	rilpivirine
155	3A457	risperidone
156	3A457	ritonavir
157	3A457	rivaroxaban
158	3A457	roflumilast
159	3A457	rolapitant
160	3A457	romidepsin
161	2C9	rosiglitazone
162	3A457	rucaparib
163	3A457	ruxolitinib
164	2C9	s-warfarin
165	3A457	salmeterol
166	3A457	saquinavir
167	2B6	selegiline
168	3A457	selexipag
169	3A457	sildenafil
170	3A457	simeprevir
171	3A457	simvastatin
172	3A457	sirolimus
173	3A457	sonidegib
174	2B6	sorafenib
175	3A457	sorafenib
176	3A457	sunitinib
177	2C9	suprofen
178	3A457	suvorexant
179	3A457	tacrolimus(fk506)
180	2C9	tamoxifen
181	3A457	tamoxifen
182	3A457	tasimelteon
183	3A457	taxol
184	3A457	telaprevir
185	3A457	telithromycin
186	3A457	terfenadine
187	3A457	testosterone
188	3A457	ticagrelor
189	3A457	tofacitinib
190	2C9	tolbutamide
191	3A457	tolvaptan
192	3A457	torisel
193	2C9	torsemide
194	2B6	tramadol
195	3A457	tramadol
196	3A457	trazodone
197	3A457	valbenazine
198	2C9	valproic acid
199	3A457	vandetanib
200	2B6	velpatasvir
201	3A457	velpatasvir
202	3A457	vemurafenib
203	3A457	venetoclax
204	2C9	venlafaxine
205	3A457	venlafaxine
206	3A457	verapamil
207	3A457	vilazodone
208	3A457	vincristine
209	3A457	vorapaxar
210	2C9	voriconazole
211	3A457	voriconazole
212	2C9	zafirlukast
213	3A457	zaleplon
214	3A457	ziprasidone
215	3A457	zolpidem

will decrease nevirapine effect

#

enzyme

inducers

nevirapine will not affect

Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.