The following drugs will decrease clobazam effect

#	enzyme	inducers
0	3A457	barbiturates
1	3A457	brigatinib
2	2C19	carbamazepine
3	3A457	carbamazepine
4	3A457	clobazam
5	3A457	dabrafenib
6	2C19	efavirenz
7	3A457	efavirenz
8	2C19	enzalutamide
9	3A457	elagolix
10	3A457	enzalutamide
11	2C19	letermovir
12	3A457	eslicarbazepine
13	2B6	artemisinin
14	3A457	glucocorticoids
15	3A457	letermovir
16	3A457	lorlatinib
17	3A457	modafinil
18	3A457	nevirapine
19	3A457	oxcarbazepine
20	2C19	norethindrone
21	3A457	perampanel
22	2C19	prednisone
23	2C19	rifampicin
24	3A457	phenobarbital
25	2C19	ritonavir
26	3A457	phenytoin
27	3A457	pioglitazone
28	3A457	rifabutin
29	3A457	rifampin
30	3A457	St. John's Wort
31	3A457	telotristat
32	3A457	troglitazone
33	3A457	vemurafenib
34	2B6	carbamazepine
35	2B6	dabrafenib
36	2B6	efavirenz
37	2B6	letermovir
38	2B6	nevirapine
39	2B6	perampanel
40	2B6	phenobarbital
41	2B6	phenytoin
42	2B6	rifampin
43	2B6	roflumilast

the follwing drugs will Increase clobazam effect

#	enzyme	Inhibitors	level
0	3A457	amiodarone	under review
1	3A457	aprepitant	Moderate inhibitor
2	2C19	armodafinil	Weak inhibitor
3	3A457	atomoxetine
4	3A457	boceprevir	under review
5	3A457	ceritinib	Strong inhibitor
6	2C19	chloramphenicol	In-Vitro Only
7	3A457	chloramphenicol	In-Vitro Only
8	2C19	cimetidine	Weak inhibitor
9	3A457	cimetidine
10	3A457	ciprofloxacin	under review
11	2C19	citalopram	Weak inhibitor
12	3A457	clarithromycin	Strong inhibitor
13	2B6	clopidogrel	Weak inhibitor
14	3A457	crizotinib	Moderate inhibitor
15	3A457	delaviridine	under review
16	3A457	diethyl-dithiocarbamate
17	3A457	diltiazem	Moderate inhibitor
18	3A457	entrectinib
19	3A457	erythromycin	Moderate inhibitor
20	2C19	esomeprazole	Weak inhibitor
21	3A457	esomeprazole
22	2C19	felbamate	Weak inhibitor
23	2C19	fluconazole	Moderate inhibitor
24	3A457	fluconazole	Moderate inhibitor
25	2C19	fluoxetine	Moderate inhibitor
26	2C19	fluvoxamine	Strong inhibitor
27	3A457	fluvoxamine	under review
28	3A457	gestodene	under review
29	3A457	grapefruit juice	Moderate inhibitor
30	3A457	idelalisib	Strong inhibitor
31	3A457	imatinib	under review
32	3A457	indinavir	Strong inhibitor
33	2C19	isoniazid	Weak inhibitor
34	3A457	itraconazole	Strong inhibitor
35	3A457	ivacaftor
36	2C19	ketoconazole	Moderate inhibitor
37	3A457	ketoconazole	Strong inhibitor
38	3A457	lesinurad
39	3A457	letermovir
40	2C19	luliconazole	Weak inhibitor
41	3A457	mibefradil	Strong inhibitor
42	3A457	mifepristone	under review
43	2C19	modafinil	Weak inhibitor
44	3A457	nefazodone	Strong inhibitor
45	3A457	nelfinavir	Strong inhibitor
46	3A457	netupitant/palonosetron	Moderate inhibitor
47	3A457	norfloxacin	under review
48	3A457	norfluoxetine	under review
49	2C19	omeprazole	Weak inhibitor
50	3A457	omeprazole	Weak inhibitor
51	2C19	oral contraceptives	Weak inhibitor
52	2C19	oritavancin	In-Vitro Only
53	2C19	pantoprazole	Weak inhibitor
54	3A457	pantoprazole
55	3A457	perampanel
56	2C19	quercetin	In-Vitro Only
57	3A457	quercetin
58	3A457	regorafenib	under review
59	3A457	ribociclib	Strong inhibitor
60	3A457	ritonavir	Strong inhibitor
61	3A457	rucaparib
62	3A457	saquinavir	Strong inhibitor
63	3A457	simeprevir
64	3A457	starfruit	under review
65	3A457	telaprevir	under review
66	3A457	telithromycin	Strong inhibitor
67	2B6	thiotepa	Weak inhibitor
68	3A457	ticagrelor
69	2B6	ticlopidine	Strong inhibitor
70	2C19	ticlopidine	Strong inhibitor
71	2C19	topiramate	under review
72	3A457	tucatinib	Strong inhibitor
73	3A457	verapamil	Moderate inhibitor
74	2B6	voriconazole	Moderate inhibitor
75	2C19	voriconazole	Moderate inhibitor
76	3A457	voriconazole	Strong inhibitor

The follwing drugs will Increase effect by clobazam effect

#	enzyme	drug	level
1	2D6	alprenolol
2	2D6	amitriptyline
3	2D6	amphetamine
4	2D6	atomoxetine
5	2D6	brexpiprazole
6	2D6	bufuralol
7	2D6	cariprazine
8	2D6	carvedilol
9	2D6	chlorpheniramine
10	2D6	chlorpromazine
11	2D6	citalopram
12	2D6	clomipramine
13	2D6	clonidine
14	2D6	codeine
15	2D6	debrisoquine
16	2D6	desipramine
17	2D6	deutetrabenazine
18	2D6	dexfenfluramine
19	2D6	dextromethorphan
20	2D6	donepezil
21	2D6	doxepin
22	2D6	eliglustat
23	2D6	encainide
24	2D6	escitalopram
25	2D6	flecainide
26	2D6	fluoxetine
27	2D6	fluvoxamine
28	2D6	ibrutinib
29	2D6	imipramine
30	2D6	lidocaine
31	2D6	metoclopramide
32	2D6	metoprolol
33	2D6	mexiletine
34	2D6	minaprine
35	2D6	nebivolol
36	2D6	nortriptyline
37	2D6	ondansetron
38	2D6	oxycodone
39	2D6	paroxetine
40	2D6	perhexiline
41	2D6	perphenazine
42	2D6	phenacetin
43	2D6	pimavanserin
44	2D6	ponatinib
45	2D6	promethazine
46	2D6	propafenone
47	2D6	propranolol
48	2D6	risperidone
49	2D6	rucaparib
50	2D6	sparteine
51	2D6	tamoxifen
52	2D6	tetrabenzine
53	2D6	thioridazine
54	2D6	timolol
55	2D6	tramadol
56	2D6	umeclidinium
57	2D6	valbenazine
58	2D6	venlafaxine
59	2D6	vilazodone
60	2D6	zuclopenthixol

The following drugs will decreased effect by clobazam effect

#	enzyme	drug
1	3A457	abemaciclib
2	3A457	abiraterone
3	3A457	acalabrutinib
4	3A457	alectinib
5	3A457	alfentanil
6	3A457	alprazolam
7	3A457	amitriptyline
8	3A457	amlodipine
9	3A457	apixaban
10	3A457	aprepitant
11	3A457	aripiprazole
12	3A457	astemizole
13	3A457	atorvastatin
14	3A457	avanafil
15	3A457	axitinib
16	3A457	boceprevir
17	3A457	bosutinib
18	3A457	brexpiprazole
19	3A457	brigatinib
20	3A457	buspirone
21	3A457	cafergot
22	3A457	caffeine
23	3A457	carbamazepine
24	3A457	cariprazine
25	3A457	ceritinib
26	3A457	cerivastatin
27	3A457	chlorpheniramine
28	3A457	cilostazol
29	3A457	cisapride
30	3A457	citalopram
31	3A457	clarithromycin
32	3A457	clobazam
33	3A457	clopidogrel
34	3A457	cobimetinib
35	3A457	cocaine
36	3A457	codeine
37	3A457	colchicine
38	3A457	copanlisib
39	3A457	crizotinib
40	3A457	cyclosporine
41	3A457	dabrafenib
42	3A457	daclatasvir
43	3A457	dapsone
44	3A457	deflazacort
45	3A457	dexamethasone
46	3A457	dextromethorphan
47	3A457	diazepam
48	3A457	diltiazem
49	3A457	docetaxel
50	3A457	dolutegravir
51	3A457	domperidone
52	3A457	doxepin
53	3A457	elagolix
54	3A457	elbasvir/grazoprevir
55	3A457	eliglustat
56	3A457	enzalutamide
57	3A457	eplerenone
58	3A457	erythromycin2
59	3A457	escitalopram
60	3A457	esomeprazole
61	3A457	estradiol
62	3A457	felodipine
63	3A457	fentanyl
64	3A457	finasteride
65	3A457	flibanserin
66	3A457	gleevec
67	3A457	haloperidol
68	3A457	hydrocortisone
69	3A457	ibrutinib
70	3A457	idelalisib
71	3A457	indacaterol
72	3A457	indinavir
73	3A457	irinotecan
74	3A457	isavuconazonium
75	3A457	ivabradine
76	3A457	ivacaftor
77	3A457	LAAM
78	3A457	lansoprazole
79	3A457	lenvatinib
80	3A457	lercanidipine
81	3A457	lidocaine
82	3A457	linagliptin
83	3A457	lovastatin
84	3A457	macitentan
85	3A457	mavacamten
86	3A457	methadone
87	3A457	midazolam
88	3A457	naldemedine
89	3A457	naloxegol
90	3A457	nateglinide
91	3A457	nelfinavir
92	3A457	neratinib
93	3A457	netupitant/palonosetron
94	3A457	nevirapine
95	3A457	nifedipine
96	3A457	nirmatrelvir
97	3A457	nisoldipine
98	3A457	nitrendipine
99	3A457	olaparib
100	3A457	omeprazole
101	3A457	ondansetron
102	3A457	osimertinib
103	3A457	ospemifene
104	3A457	palbociclib
105	3A457	panobinostat
106	3A457	pantoprazole
107	3A457	perampanel
108	3A457	pimavanserin
109	3A457	pimozide
110	3A457	pomalidomide
111	3A457	ponatinib
112	3A457	progesterone
113	3A457	propranolol
114	3A457	quetiapine
115	3A457	quinidine
116	3A457	quinine
117	3A457	regorafenib
118	3A457	ribociclib
119	3A457	rilpivirine
120	3A457	risperidone
121	3A457	ritonavir
122	3A457	rivaroxaban
123	3A457	roflumilast
124	3A457	rolapitant
125	3A457	romidepsin
126	3A457	rucaparib
127	3A457	ruxolitinib
128	3A457	salmeterol
129	3A457	saquinavir
130	3A457	selexipag
131	3A457	sildenafil
132	3A457	simeprevir
133	3A457	simvastatin
134	3A457	sirolimus
135	3A457	sonidegib
136	3A457	sorafenib
137	3A457	sunitinib
138	3A457	suvorexant
139	3A457	tacrolimus(fk506)
140	3A457	tamoxifen
141	3A457	tasimelteon
142	3A457	taxol
143	3A457	telaprevir
144	3A457	telithromycin
145	3A457	terfenadine
146	3A457	testosterone
147	3A457	ticagrelor
148	3A457	tofacitinib
149	3A457	tolvaptan
150	3A457	torisel
151	3A457	tramadol
152	3A457	trazodone
153	3A457	valbenazine
154	3A457	vandetanib
155	3A457	velpatasvir
156	3A457	vemurafenib
157	3A457	venetoclax
158	3A457	venlafaxine
159	3A457	verapamil
160	3A457	vilazodone
161	3A457	vincristine
162	3A457	vorapaxar
163	3A457	voriconazole
164	3A457	zaleplon
165	3A457	ziprasidone
166	3A457	zolpidem

will decrease clobazam effect

#

enzyme

inducers

clobazam will not affect

Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.