ESMOLOL

Brand Name & Strength

Esocard 100 mg/10 ml

Reconstitution

Not required

Further Dilution

Not required

Diluent

Not required

Administration & Infusion rate

IV only

Supraventricular tachycardia: Infuse loading dose (500 mcg/kg/min) over 1 min followed by a 4 min maintenance infusion of required dose (50 mcg/kg/min) (max dose: 200 mcg/kg/min for 24 – 48 hr)

Sinus tachycardia or hypertension: Initially, administer 80 mg (1 mg/kg) by

IV bolus

over 30 sec; then if needed, 150 mcg/kg/min by

IV infusion

to a maximum of 300 mcg/kg/min

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

-

After dilution

24 hr

Remarks

Incompatible: NaHCO3 (5%)

Avoid infusions (concentration > 10mg/ml) into small veins or use of butterfly catheters (cause thrombophlebitis)

Do not stop abruptly, possibility of withdrawal effect

Intended for short-term use, not longer than 48 hours