ALPROSTADIL

Brand Name & Strength

Prostin VR Pediatric 500 mcg/1 ml

Reconstitution

Not required

Further Dilution

See

Administration & Infusion rate

Diluent

NS, D5

Administration & Infusion rate

Continuous

IV infusion

only (max concentration 20 mcg/ml) Maximum rate: 0.4 mcg/kg/min Add 1 ampoule (500 mcg) Alprostadil to: Approximate concentration of resulting solution (mcg/ml) Infusion rate (ml/min/kg of body weight)

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

- -

After dilution

24 hr -

Remarks

Undiluted solution may interact with sidewalls of volumetric infusion chambers causing changes in appearance of the chamber and creating a hazy solution.

Avoid direct contact of undiluted solution the walls of volumetric infusion chamber by adding it into the intravenous infusion solution.

Administer through central line or through umbilical artery catheter placed at the ductal opening.