AMPICILLIN

Brand Name & Strength

Standacillin® Injection 500 mg

Reconstitution

Reconstitute 1 vial with 5 ml of WFI

Further Dilution

IV infusion

Dilute the reconstituted solution to any amount of diluent

Dilute 500 – 1000 mg in 50 ml diluent or 2000 mg in 100 ml diluent (max concentration: 30 mg/ml)

Diluent

NS

Administration & Infusion rate

IM

Administer the reconstituted solution through IM into large muscle mass. Slow IV

Administer the reconstituted solution over 3 – 5 min (250 – 500 mg) or over 10 – 15 min (1 – 2 g). Do not exceed 100 mg/min.

IV infusion

Administer over 15 – 30 min

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

Use immediately Discard unused portion -

After dilution

- -

Remarks

Be aware that too-rapid infusion may cause seizures.

Adjust rate of infusion so that the total dose is administered before admixture stability expires.

Maximum concentration for infusion should not exceed 30 mg/ml due to concentration – dependent stability restrictions.