OXYTOCIN
Brand Name & Strength
Udoxan Injection 10 IU/ml
Reconstitution
Not required
Further Dilution
IV infusion
Induction and Enhancement of Labour
Dilute 10 IU to 1000 ml diluent to yield Oxytocin 0.01 IU/ml (10 mIU/ml)
Postpartum uterine bleeding
Dilute 10 – 40 IU to running
IV infusion
, max: 40 IU/1000 ml
Diluent
NS [1,2,3,4], or lactated Ringer’s solution
Administration & Infusion rate
IV infusion
For induction and enhancement of labour
Administer at 1 – 4 mIU/min (0.1 – 0.4 ml/min or 2 – 8 drops/min). Increase rate gradually at
intervals of not shorter than 20 min. Max rate: 20 mIU/min (2 ml/min or 40 drops/min)
For postpartum bleeding
Administer 10 – 40 IU at a rate sufficient to sustain uterine contraction and control uterine atony.
IM
Administer 10 IU after delivery
Storage & Stability
RT
(<25 oC)
Fridge
(2 – 8 oC)
After Reconstitution
-
-
After dilution
-
-
Remarks
IV bolus
for more than 2 I.U can cause acute hypotension
Use of D5 is not recommended. Not compatible with solutions containing bisulphites and
metasulphites as preservatives
Do not exceed 30 IU in 12-hr period because of risk of water intoxication