AMIKACIN

AMIKACIN

Brand Name & Strength

Apalin 100 mg/2 ml, 250 mg /2 ml & 500 mg/2 ml

Reconstitution

Not required

Further Dilution

IV infusion

  • Dilute in 100 – 200 ml diluent (concentration: 0.25 – 5 mg/ml)

    Diluent

    NS, D5, lactated Ringer’s Solution

    Administration & Infusion rate

    IM
  • Administer into large muscle mass

    IV infusion

  • Administer slowly over 30 – 60 min for children, adolescents and adults; 1 – 2 hr for infants [2,3]

    Storage & Stability

    RT

    (<25 oC)

    Fridge

    (2 – 8 oC)

    After Reconstitution

    - -

    After dilution

    24 hr 60 days

    Remarks

  • Slow infusion may help to avoid neuromuscular blockade
  • Discard dark-coloured solutions