AMIKACIN

Brand Name & Strength

Apalin 100 mg/2 ml, 250 mg /2 ml & 500 mg/2 ml

Reconstitution

Not required

Further Dilution

IV infusion

Dilute in 100 – 200 ml diluent (concentration: 0.25 – 5 mg/ml)

Diluent

NS, D5, lactated Ringer’s Solution

Administration & Infusion rate

IM

Administer into large muscle mass

IV infusion

Administer slowly over 30 – 60 min for children, adolescents and adults; 1 – 2 hr for infants [2,3]

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

- -

After dilution

24 hr 60 days

Remarks

Slow infusion may help to avoid neuromuscular blockade

Discard dark-coloured solutions