MESNA

Brand Name & Strength

Uromitexan 400 mg/4 ml

Reconstitution

Not required

Further Dilution

IV infusion

Dilute to a final concentration of 20 mg/ml

Diluent

NS, D5, lactated Ringer’s solution

Administration & Infusion rate

IV bolus

Administer over 1 min

IV infusion

Administer over 15 min Continuous

IV infusion

Administer over 12 – 24 hr after completion of ifosfamide infusion Refer to specific protocol for administration rate/details

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

- -

After dilution

24 hr -

Remarks

Maintain adequate hydration and urinary output during ifosfamide treatment