CEFOPERAZONE

CEFOPERAZONE

Brand Name & Strength

Bicafar 500 mg, 1000 mg, 2000 mg

Reconstitution

Reconstitute with 5 ml of D5, NS, D10, WFI

Further Dilution

Slow IV
  • Dilute reconstituted solution with 20 – 100 ml diluent

    IV infusion

  • Dilute the reconstituted solution with 20 – 100 ml diluent IM
  • WFI should be used when preparing Cefoperazone. However, when concentration of more than 250 mg/ml a lidocaine solution should be used

    Diluent

    NS, D5, D10, lactated Ringer’s solution

    Administration & Infusion rate

    IV infusion

  • Administer over 15 min – 1 hr Slow IV
  • Administer over 3 – 5 min IM

    Storage & Stability

    RT

    (<25 oC)

    Fridge

    (2 – 8 oC)

    After Reconstitution

    24 hr 5 days

    After dilution

    Remarks

  • Cefoperazone is incompatible with aminoglycosides, perphenazine or pethidine hydrochloride
  • When given by IM, inject into large muscle mass of gluteus maximum or anterior thigh