BASILIXIMAB

Brand Name & Strength

Simulect® 20 mg

Reconstitution

Reconstitute with 5 ml of WFI

Further Dilution

IV infusion

Dilute to a volume of 50 ml of diluent

Diluent

NS, D5

Administration & Infusion rate

IV bolus

[1,2,3]

IV infusion

Administer over 20 – 30 minutes [1,2,3]

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

4 hr 24 hr

After dilution

- -

Remarks

Given via central or peripheral IV route only

Do not infuse with other drugs simultaneously in the same IV line

Bolus dosing is associated with nausea, vomiting and local pain on the injection site

When mixing the solution, gently invert the bag in order to avoid foaming; DO NOT SHAKE.