IRON SUCROSE

Brand Name & Strength

Venofer 100 mg/5 ml

Reconstitution

Not required

Further Dilution

IV infusion

Dilute 100 mg (5 ml) in 100 ml of diluent

Dilute 500 mg (25 ml) in 500 ml of diluent

Diluent

NS

Administration & Infusion rate

Test Dose Weight Test Dose Children (<14 kg) 1.5 mg iron/kg Children (>14 kg) & Adult 1 ml (20 mg) Administration

IV drip infusion The first 20 mg iron of the therapeutic dose should be infused over 15 min as a test dose.

Slow IV injection Administer 1 ml by slow IV over 1 – 2 min and observe for 15 min.

IV injection (undiluted)

Administer 100 mg iron (5 ml) in at least over 5 min or 200 mg iron (10 ml) over 10 min.

As injection, maximum tolerated dose per day, given not more than 3 times per week: 200 mg iron (10 ml) injected over at 10 min.

As infusion, maximum tolerated single dose per day given NOT more than once per week

Storage & Stability

RT

(23 – 27 oC)

Fridge

(2 – 8 oC)

After Reconstitution

- -

After dilution

7 days

Remarks

Venofer must only be mixed with sterile 0.9% m/V Sodium Chloride solution

Compatibility with containers other than glass, polyethylene and PVC is not known

The diluted solution must appear as brown and clear solution