In Dupuytren’s contracture, the fibrous tissue in the palm of the hand becomes thickened and forms lumps (nodules) under the skin. The nodules form cords of tissue that gradually shorten, causing one or more fingers to bend in toward the palm.
The condition may occur in one or both hands and most commonly affects the fourth and fifth fingers. It is usually painless. The tissue changes usually develop slowly, over months or years.The cause of Dupuytren’s contracture is unknown, although the condition sometimes runs in families.
In many cases, the condition is mild, has little impact on the function of the hand, and does not need treatment.
If treatment is needed, it may involve radiation therapy to the hand, injections of an enzyme into the thickened tissue, or cutting the thickened tissue by inserting a needle or blade though the skin.
In severe cases, open surgery to cut or remove the thickened tissue may be necessary

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