Pancreatin
CLINICAL USE
Pancreatic enzyme replacement
DOSE IN NORMAL RENAL FUNCTION
1–6 capsules (depends on preparation) with meals, adjusted according to response(1 capsule if using the strong preparation)
PHARMACOKINETICS
Molecular weight                           :No data %Protein binding                           :No data %Excreted unchanged in urine     : No data Volume of distribution (L/kg)       :No datahalf-life – normal/ESRD (hrs)      :No data DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
20 to 50     : Dose as in normal renal function 10 to 20     : Dose as in normal renal function <10           : Dose as in normal renal function DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
CAPD                :Unlikely to be dialysed. Dose as in normal renal function HD                     :Unlikely to be dialysed. Dose as in normal renal functionHDF/high flux   :Unlikely to be dialysed. Dose as in normal renal functionCAV/VVHD      :Unlikely to be dialysed. Dose as in normal renal function IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugsNone known ADMINISTRATION
Reconstition
– Route
Oral Rate of Administration
–Comments
– OTHER INFORMATION
Not absorbed from GI tract .
See how to identify renal failure stages according to GFR calculation
See how to diagnose irreversible renal disease
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