ZIDOVUDINE

Brand Name & Strength

Retrovir ™ 200 mg/20 ml

Reconstitution

Not required

Further Dilution

Dilute with diluent to a concentration of 2 mg/ml (max concentration: 4 mg/ml)

Diluent

D5

Administration & Infusion rate

IV infusion

Administer over 1 hr Prevention of maternal-fetal HIV transmission: Administer loading dose over 1 hr followed by continuous

IV infusion

of 1 mg/kg/hr until delivery

Storage & Stability

RT

(<25 oC)

Fridge

(2-8 oC)

After Reconstitution

- -

After dilution

48 hr 48 hr

Remarks

Avoid rapid infusion or bolus injection Do not administer IM Administer within 8 hr if stored at 25 C or within 24 hours if refrigerated at 2 – 8 C