PENTAMIDINE ISETHIONATE
Brand Name & Strength
DBL Pentamidine Isethionate 300 mg
Reconstitution
Reconstitute 300 mg vial in 3 – 5 ml WFI
Further Dilution
Dilute the required dose in 50 – 250 ml diluent
Diluent
D5, NS
Administration & Infusion rate
IV infusion
Administer over at least 60 – 120 min
Storage & Stability
RT
(<25 oC)
Fridge
(2-8 oC)
After Reconstitution
48 hr
48 hr
After dilution
Solution diluted to 1 – 2.5 mg/ml
in diluent: 24 hr
-
Remarks
Injection should be given as a slow
IV infusion
with patient in a supine position in order to reduce the
incidence of sudden severe hypotension
Direct
IV bolus
or rapid administration must not be used