INFLIXIMAB

INFLIXIMAB

Brand Name & Strength

Remicade 100 mg

Reconstitution

Reconstitute with 10 ml of WFI (Concentration: 10 mg/ml)

Further Dilution

Dilute the reconstituted solution with diluent to obtain a total infusion volume of 250 ml (Concentration: 0.4 – 4 mg/ml)

Diluent

NS

Administration & Infusion rate

IV infusion

  • Administer over at least 2 hr (max rate: 2 ml/min)

    Storage & Stability

    RT

    (<25 oC)

    Fridge

    (2 – 8 oC)

    After Reconstitution

    3 hr 24 hr

    After dilution

    3 hr 24 hr

    Remarks

  • The solution is colourless to light yellow and opalescent
  • The solution may develop a few fine translucent particles, as infliximab is a protein
  • Do not use if opaque particles, discoloration, or other foreign particles
  • Do not infuse in same IV line as other agents
  • Use an infusion set with an in-line filter, with pore size of 1.2 micrometer or less