ILOPROST

Brand Name & Strength

Ilomedin 0.5 ml (contains 67 mcg Iloprost Trometamol equivalent to 50 mcg Iloprost)

Reconstitution

Not required

Further Dilution

For infusion pump use

Dilute 50 mcg (0.5 ml) with 250 ml diluent to a final concentration of 0.2 mcg/ml For syringe driver use

Dilute 50 mcg (0.5 ml) with 25 ml diluent to a final concentration of 2 mcg/ml

Diluent

NS, D5

Administration & Infusion rate

IV infusion

Administer over 6 hr via a peripheral vein or a central venous catheter.

Treatment can be started at an infusion rate to deliver 0.5 ng/kg/min for 30 min. The dose can then be increased at intervals of about 30 min in steps of 0.5 ng/kg/min up to 2 ng/kg/min. (Refer to product leaflet for the table that consists of infusion rate corresponding to weight.)

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

-

After dilution

-

Remarks

Ilomedin must be administered

After dilution

.

The infusion solution should be made up freshly each day to ensure sterility.