What HEMATO POLYVALENT SNAKE ANTIVENIN is used for




HEMATO POLYVALENT SNAKE ANTIVENIN

HEMATO POLYVALENT SNAKE ANTIVENIN

Brand Name & Strength

Polyvalent Snake Antivenin 1 ml which contains: Russell’s Viper Venom (0.6mg), Green Pit Viper Venom (0.7mg), Malayan Pit Viper Venom (1.6mg)

Reconstitution

Reconstitute with 10 ml of WFI

Further Dilution

Dilute the reconstituted antivenom with 5 – 10 ml/kg diluent for children or 250 – 500 ml diluent for adult

Diluent

NS, D5

Administration & Infusion rate

IV infusion

  • Initial dose is 30 ml (3 vials)
  • Administer at 1 – 2 ml/min over 10 – 15 min. If no reaction, complete the infusion at a rate of 5 – 10 ml/min within less than 1 hr. If active bleeding still persist, the second dose can be administered after 2 hr or earlier.
  • Subsequent dose can be given every 6 hr according to clinical signs and symptoms.

    Storage & Stability

    RT

    (<25 oC)

    Fridge

    (2 – 8 oC)

    After Reconstitution

    Use immediately -

    After dilution

    Use immediately -

    Remarks

  • Gently swirl until serum become clear colourless or pale yellow liquid
  • Observe for any anaphylaxis and delay serum sickness reactions.
  • Skin test should be performed prior administration to avoid serious allergic reaction.