What GLYCERYL TRINITRATE is used for




GLYCERYL TRINITRATE

GLYCERYL TRINITRATE

Brand Name & Strength

Gitrinil Injection 50 mg/10 ml

Reconstitution

Not required

Further Dilution

IV infusion

  • Dilute 50 mg in 500 ml diluent (100 mcg/ml)
  • Dilute 50 mg in 250 ml diluent. Alternatively use 10 mg in 50 ml diluent (200 mcg/ml)
  • Max concentration: 400 mcg/ml

    Diluent

    D5, NS

    Administration & Infusion rate

    IV infusion

  • Initially administer 5 mcg/min, increase by 5 mcg/min every 3 – 5 min to 20 mcg/min [1,2,3]
  • If no response, increase by 10 mcg/min every 3 – 5 min to 20 mcg/min [1,2,3]

    Storage & Stability

    RT

    (<25 oC)

    Fridge

    (2 – 8 oC)

    After Reconstitution

    40 hr 7 days

    After dilution

    40 hr 7 days

    Remarks

  • Not to be used undiluted [1,2,3]
  • Invert the glass parenteral bottle several times following admixture to assure uniform dilution
  • Dilution and storage of GTN for

    IV infusion

    should be done only in glass parenteral solution bottles