ADRENALINE

ADRENALINE

Brand Name & Strength

CCM Adrenaline Injection 1 mg/ml

Reconstitution

Not required

Further Dilution

IV infusion

  • Dilute 1 mg up to 250 ml diluent (concentration: 4 mcg/ml)
  • Single strength: Dilute 3 mg in 50 ml diluent (concentration: 60 mcg/ml)
  • Double strength: Dilute 6 mg in 50 ml diluent (concentration: 120 mcg/ml)

    Diluent

    NS, D5

    Administration & Infusion rate

    IM, SC
  • Use undiluted Slow IV
  • Use undiluted. Administer 1 mg dose over at least 1 min

    IV infusion

  • Bradycardia, hypotension / shock: Administer at 2 – 10 mcg/min or 0.1 - 0.5 mcg/kg/min (7 – 35 mcg/min)
  • Bronchodilation, anaphylaxis, hypersensitivity reaction: Administer at 1 mcg/min up to 10 mcg/min. Titrate up per response

    Storage & Stability

    RT

    (<25 oC)

    Fridge

    (2-8 oC)

    After Reconstitution

    - -

    After dilution

    - -

    Remarks

  • CCM Adrenaline contains Sodium Metabisulphite that may cause serious allergic type reactions.
  • Rapidly denatured by oxidising agents and alkalis including sodium bicarbonate, halogens, nitrates, nitrites and salts of iron, copper and zinc
  • Incompatible with 5% Sodium Chloride
  • Central line required for

    IV infusion

    administration
  • Stability of Adrenaline in 5% dextrose injection decreases when pH >5.5