ADRENALINE

Brand Name & Strength

CCM Adrenaline Injection 1 mg/ml

Reconstitution

Not required

Further Dilution

IV infusion

Dilute 1 mg up to 250 ml diluent (concentration: 4 mcg/ml)

Single strength: Dilute 3 mg in 50 ml diluent (concentration: 60 mcg/ml)

Double strength: Dilute 6 mg in 50 ml diluent (concentration: 120 mcg/ml)

Diluent

NS, D5

Administration & Infusion rate

IM, SC

Use undiluted Slow IV

Use undiluted. Administer 1 mg dose over at least 1 min

IV infusion

Bradycardia, hypotension / shock: Administer at 2 – 10 mcg/min or 0.1 - 0.5 mcg/kg/min (7 – 35 mcg/min)

Bronchodilation, anaphylaxis, hypersensitivity reaction: Administer at 1 mcg/min up to 10 mcg/min. Titrate up per response

Storage & Stability

RT

(<25 oC)

Fridge

(2-8 oC)

After Reconstitution

- -

After dilution

- -

Remarks

CCM Adrenaline contains Sodium Metabisulphite that may cause serious allergic type reactions.

Rapidly denatured by oxidising agents and alkalis including sodium bicarbonate, halogens, nitrates, nitrites and salts of iron, copper and zinc

Incompatible with 5% Sodium Chloride

Central line required for

IV infusion

administration

Stability of Adrenaline in 5% dextrose injection decreases when pH >5.5