In chronic kidney disease, there is a gradual and progressive loss of function affecting both kidneys. It is usually caused by a long-term condition, such as high blood pressure, diabetes, kidney infection, or longstanding obstruction to urine flow—for example, due to an enlarged prostate gland .
It may also occur with prolonged use of some medications and the inherited disorder polycystic kidney disease. Chronic kidney disease typically produces few symptoms until it is advanced, when tiredness; weakness; nausea; itching; blood in the urine; and swelling of the ankles, feet, or hands may occur.
Treatment is directed at the underlying cause. In severe cases, dialysis or a kidney transplant may be needed.

Othere related diseases

FIBROIDS
Fibroids are slow-growing, noncancerous growths in the uterus that consist of muscle and fibrous tissue. Their cause is unknown, although they are thought to be...

GENITAL HERPES
Genital herpes is caused by infection with the herpes simplex virus. The virus is spread by close contact with the skin or moist membranes.
A mother may a...

GENITAL WARTS
Genital warts are small, fleshy growths on or around the genitals or anal area caused by infection with certain strains of human papillomavirus (HPV). The virus...

GONORRHEA
Gonorrhea is a sexually transmitted disease caused by the bacterium Neisseria gonorrhoeae. It can also be transmitted from a mother to her baby during birth. Go...

GYNECOMASTIA
Gynecomastia is a noncancerous enlargement of one or both breasts in men or boys. It is often due to an excess of the female hormone estrogen (which is also pro...

HYDROCELE
A hydrocele is a soft, painless swelling in the scrotum that is due to a build-up of fluid in the double-layered membrane that partially surrounds each testis. ...

KIDNEY CANCER
Most kidney cancers originate within the kidney itself; only rarely are they due to the spread of cancer from elsewhere in the body. There are often no symptoms...

KIDNEY CYSTS
Simple kidney cysts are fluid-filled sacs that develop in the outer layer of the kidney. They can occur singly or multiply, and one or both kidneys may be a...