Primary biliary cholangitis Cholangitis is inflammation of the bile ducts, the tubes that carry bile from the liver to the gallbladder and intestines. It is usually caused by bacterial infection, often as a result of blockage of a bile duct, and typically causes upper abdominal pain, fever, chills, nausea, vomiting, and jaundice. Treatment is with antibiotics and, if necessary, surgery to clear any blockage.
Primary biliary cholangitis is a long-term condition in which the bile ducts become damaged. It is thought to be due to the immune system mistakenly attacking the ducts. Symptoms include tiredness, itchy skin, and bloating.
Treatment may include medication to minimize liver damage and relieve symptoms. In severe cases, a liver transplant may be needed.

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