nystatin
CLINICAL USE
Antifungal agent
DOSE IN NORMAL RENAL FUNCTION
Oral: 100 000–1 000 000 units (1–10 mL) every 6 hoursTopical: Apply 2–4 times daily (depends on formulation)
PHARMACOKINETICS
Molecular weight                           :926.1 %Protein binding                           :No data %Excreted unchanged in urine     : No data Volume of distribution (L/kg)       :No datahalf-life – normal/ESRD (hrs)      :No data DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
20 to 50     : Dose as in normal renal function 10 to 20     : Dose as in normal renal function <10           : Dose as in normal renal function DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
CAPD                :Not dialysed. Dose as in normal renal function HD                     :Not dialysed. Dose as in normal renal functionHDF/high flux   :Not dialysed. Dose as in normal renal functionCAV/VVHD      :Not dialysed. Dose as in normal renal function IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugsNone known ADMINISTRATION
Reconstition
– Route
Oral, topical Rate of Administration
–Comments
– OTHER INFORMATION
Not absorbed from intact skin or mucous membranesNo significant gastrointestinal absorption
See how to identify renal failure stages according to GFR calculation
See how to diagnose irreversible renal disease
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