Antifungal agent: Invasive candidiasis

200 mg loading dose then 100 mg daily Oesophageal candidiasis: 100 mg loading dose then 50 mg daily

Molecular weight : 1140.2

%Protein binding : >99

%Excreted unchanged in urine : <1

Volume of distribution (L/kg) : 30–50 litres

half-life – normal/ESRD (hrs) : 40–50/Unchanged

20 to 50 : Dose as in normal renal function

10 to 20 : Dose as in normal renal function

<10 : Dose as in normal renal function

CAPD : Not dialysed. Dose as in normal renal function

HD : Not dialysed. Dose as in normal renal function

HDF/high flux : Unlikely to be dialysed. Dose as in normal renal function

CAV/VVHD : Unlikely to be dialysed. Dose as in normal renal function

Potentially hazardous interactions with other drugs None known

With diluent provided

1.1 mg/minute (3 mL/minute)

Can be further diluted in sodium chloride 0.9% or glucose 5%. Add 100 mg to 250 mL or 200 mg to 500 mL of fluid