PIPERACILLIN

Brand Name & Strength

Tapicin Powder for Injection 4.5 g

Reconstitution

Reconstitute each vial with 20 ml of WFI, NS or D5

Further Dilution

IV infusion

Dilute with 50 – 150 ml diluent

Diluent

NS, D5, WFI

Administration & Infusion rate

IV bolus

Administer over 3 – 5 min

IV infusion

Administer over 30 min Administer over 3 – 4 hr (extended infusion)

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

24 hr 7 days

After dilution

- -

Remarks

Extended infusion has been shown to improve the time the free drug remains above MIC that predicts the killing characteristic of the antibiotic