HYALURONIDASE

Brand Name & Strength

Hyaluronidase 1500 IU Powder for Solution for Injection / Infusion

Reconstitution

Conditions

Reconstitution

SC Infusion (hypodermoclysis), Extravasation, Haematoma Dilute 1 vial in 1ml WFI or NS SC, IM Dissolve 1 vial directly in to solution to be injected Local Anaesthetics Dilute 1 vial with quantity of local anaesthetic solution to be used. 15 IU/ml is recommended in ophthalmology

Further Dilution

Not required

Diluent

SC infusion (hypodermoclysis)

NS, D5

Administration & Infusion rate

IM, SC, SC infusion

SC infusion (hypodermoclysis): Hyaluronidase injected into the site before the infusion is set up, or injected into the tubing of the infusion set, about 2 cm back from the needle, at the start of the infusion.

Extravasation: infiltrated into the affected area

Haematoma: infiltrated into the affected area

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

- -

After dilution

Immediately -

Remarks

Should not be administered by intravenous injection.