MEBZOL

Composition

Each tablet contains: Mebendazole 100 mg.
Also SUSPENSION, each teaspoonful
(5 ml) contains mebendazole 100 mg.

Indications

Mebzol is mainly indicated for the treat­ ment of single or mixed intestinal nema­tode infections caused by threadworm pinworm (Enterobius vermicularis), roundworm (Ascaris lumbricoides), whip­ worm (Trichuris trichiura), and hookworm (Ancylostoma duodenale and Necator americanus).

Contraindications

Hypersensitivity.

Side Effects

Mebzol is usually very well tolerated. Rarely, gastrointestinal disturbances including transient abdominal pain and diarrhea have been experienced, particu­ larly in patients with heavy intestinal infec­tion. Hypersensitivity reactions including exanthema, rash, urticaria, and angioede-ma have rarely been reported with use of mebendazole.

Precautions

Pregnancy and Lactation
Pregnancy: Since mebendazole crosses the placenta, caution is recommended during pregnancy, especially in the first trimester. Therefore, it is generally advis­ able to use mebendazole only if the bene­ fits to the mother justify the potential risks to the fetus. Lactation: It is better to exercise caution when mebendazole is prescribed to nurs­ing women as it is still not known whether it is excreted in breast milk.

Drug Interactions

Metabolism of mebendazole may possibly be inhibited by cimetidine. Therefore, upon concurrent administration, plasma con­ centration of mebendazole may be increased.

Dosage and Administration

General Dosage and Administration
Advice
Mebzol tablets may be chewed, swal­
lowed whole, or crushed and mixed with
food.
No special procedures (e.g. dietary restric­tion or fasting; use of laxative or cleansing enemas) are required before, during, or immediately after treatment with Mebzol.
Common Dosage Regimen
Adults and Children Over 2 Years
Threadworm/pinworm infection (entero­ biasis): 1 tablet or teaspoonful (5 ml) sus­pension given as a single dose. If re-infec­tion occurs, a second dose may be need­ed after 2 – 3 weeks.
Roundworm (ascariasis), whipworm,hookworm, and mixed infections: 1 tabletor teaspoonful (5 ml) suspension twice daily (morning and evening) for three days.
Children below 2 years: Not recommend­ed.

Packaging

sp: 30 ml
t: 6.