Formoterol fumarate
Formoterol fumarate
CLINICAL USE
Long acting selective beta-2 agonist
DOSE IN NORMAL RENAL FUNCTION
1–2 puffs twice dailyTurbohaler: 4.5–18 mcg 1–2 times daily; maximum 54 mcg daily, maximum 36 mcg daily in COPD
PHARMACOKINETICS
Molecular weight                           :804.9 %Protein binding                           :61–64 %Excreted unchanged in urine     : 6.4–8 Volume of distribution (L/kg)       :No datahalf-life – normal/ESRD (hrs)      :8/– DOSE IN RENAL IMPAIRMENT
GFR (mL/MIN)
20 to 50     : Dose as in normal renal function 10 to 20     : Dose as in normal renal function <10           : Dose as in normal renal function DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES
CAPD                :Not dialysed. Dose as in normal renal function HD                     :Unlikely to be dialysed. Dose as in normal renal functionHDF/high flux   :Unlikely to be dialysed. Dose as in normal renal functionCAV/VVHD      :Not dialysed. Dose as in normal renal function IMPORTANT DRUG INTERACTIONS
Potentially hazardous interactions with other drugsNone known ADMINISTRATION
Reconstition
– Route
Inhaled Rate of Administration
–Comments
See how to identify renal failure stages according to GFR calculation
See how to diagnose irreversible renal disease
Home