The following drugs will decrease ticlopidine effect

#

enzyme

inducers

the follwing drugs will Increase ticlopidine effect

#

enzyme

Inhibitors

level

The follwing drugs will Increase effect by ticlopidine effect

#	enzyme	drug	level
1	2D6	alprenolol	In-Vitro Only
2	2C19	amitriptyline	Strong inhibitor
3	2D6	amitriptyline	In-Vitro Only
4	2D6	amphetamine	In-Vitro Only
5	2B6	artemisinin	Strong inhibitor
6	2C19	atomoxetine	Strong inhibitor
7	2D6	atomoxetine	In-Vitro Only
8	2D6	brexpiprazole	In-Vitro Only
9	2C19	brivaracetam	Strong inhibitor
10	2D6	bufuralol	In-Vitro Only
11	2B6	bupropion	Strong inhibitor
12	2D6	cariprazine	In-Vitro Only
13	2C19	carisoprodol	Strong inhibitor
14	2D6	carvedilol	In-Vitro Only
15	2C19	celecoxib	Strong inhibitor
16	2C19	chloramphenicol	Strong inhibitor
17	2D6	chlorpheniramine	In-Vitro Only
18	2D6	chlorpromazine	In-Vitro Only
19	2C19	citalopram	Strong inhibitor
20	2D6	citalopram	In-Vitro Only
21	2C19	clobazam	Strong inhibitor
22	2B6	clobazam	Strong inhibitor
23	2C19	clomipramine	Strong inhibitor
24	2D6	clomipramine	In-Vitro Only
25	2D6	clonidine	In-Vitro Only
26	2C19	clopidogrel	Strong inhibitor
27	2D6	codeine	In-Vitro Only
28	2C19	cyclophosphamide	Strong inhibitor
29	2B6	cyclophosphamide	Strong inhibitor
30	2D6	debrisoquine	In-Vitro Only
31	2D6	desipramine	In-Vitro Only
32	2D6	deutetrabenazine	In-Vitro Only
33	2D6	dexfenfluramine	In-Vitro Only
34	2D6	dextromethorphan	In-Vitro Only
35	2C19	diazepam	Strong inhibitor
36	2D6	donepezil	In-Vitro Only
37	2C19	doxepin	Strong inhibitor
38	2D6	doxepin	In-Vitro Only
39	2B6	efavirenz	Strong inhibitor
40	2D6	eliglustat	In-Vitro Only
41	2D6	encainide	In-Vitro Only
42	2C19	escitalopram	Strong inhibitor
43	2D6	escitalopram	In-Vitro Only
44	2C19	esomeprazole	Strong inhibitor
45	2D6	flecainide	In-Vitro Only
46	2C19	flibanserin	Strong inhibitor
47	2D6	fluoxetine	In-Vitro Only
48	2D6	fluvoxamine	In-Vitro Only
49	2C19	hexobarbital	Strong inhibitor
50	2D6	ibrutinib	In-Vitro Only
51	2B6	ifosphamide	Strong inhibitor
52	2C19	imipramine	Strong inhibitor
53	2D6	imipramine	In-Vitro Only
54	2C19	indomethacin	Strong inhibitor
55	2B6	ketamine	Strong inhibitor
56	2C19	labetalol	Strong inhibitor
57	2C19	lansoprazole	Strong inhibitor
58	2D6	lidocaine	In-Vitro Only
59	2C19	mavacamten	Strong inhibitor
60	2B6	meperidine	Strong inhibitor
61	2B6	methadone	Strong inhibitor
62	2D6	metoclopramide	In-Vitro Only
63	2D6	metoprolol	In-Vitro Only
64	2D6	mexiletine	In-Vitro Only
65	2D6	minaprine	In-Vitro Only
66	2C19	moclobemide	Strong inhibitor
67	2D6	nebivolol	In-Vitro Only
68	2C19	nelfinavir	Strong inhibitor
69	2B6	nevirapine	Strong inhibitor
70	2C19	nilutamide	Strong inhibitor
71	2D6	nortriptyline	In-Vitro Only
72	2C19	omeprazole	Strong inhibitor
73	2D6	ondansetron	In-Vitro Only
74	2C19	ospemifene	Strong inhibitor
75	2D6	oxycodone	In-Vitro Only
76	2C19	pantoprazole	Strong inhibitor
77	2D6	paroxetine	In-Vitro Only
78	2D6	perhexiline	In-Vitro Only
79	2D6	perphenazine	In-Vitro Only
80	2D6	phenacetin	In-Vitro Only
81	2C19	phenobarbitone	Strong inhibitor
82	2C19	phenytoin	Strong inhibitor
83	2D6	pimavanserin	In-Vitro Only
84	2C19	pomalidomide	Strong inhibitor
85	2D6	ponatinib	In-Vitro Only
86	2C19	primidone	Strong inhibitor
87	2C19	progesterone	Strong inhibitor
88	2C19	proguanil	Strong inhibitor
89	2D6	promethazine	In-Vitro Only
90	2D6	propafenone	In-Vitro Only
91	2B6	propafol	Strong inhibitor
92	2C19	propranolol	Strong inhibitor
93	2D6	propranolol	In-Vitro Only
94	2C19	r-mephobarbital	Strong inhibitor
95	2C19	r-warfarin	Strong inhibitor
96	2D6	risperidone	In-Vitro Only
97	2D6	rucaparib	In-Vitro Only
98	2C19	s-mephenytoin	Strong inhibitor
99	2B6	selegiline	Strong inhibitor
100	2B6	sorafenib	Strong inhibitor
101	2D6	sparteine	In-Vitro Only
102	2C19	suvorexant	Strong inhibitor
103	2D6	tamoxifen	In-Vitro Only
104	2C19	teniposide	Strong inhibitor
105	2D6	tetrabenzine	In-Vitro Only
106	2D6	thioridazine	In-Vitro Only
107	2D6	timolol	In-Vitro Only
108	2C19	tofacitinib	Strong inhibitor
109	2D6	tramadol	In-Vitro Only
110	2B6	tramadol	Strong inhibitor
111	2D6	umeclidinium	In-Vitro Only
112	2D6	valbenazine	In-Vitro Only
113	2B6	velpatasvir	Strong inhibitor
114	2C19	venlafaxine	Strong inhibitor
115	2D6	venlafaxine	In-Vitro Only
116	2C19	vilazodone	Strong inhibitor
117	2D6	vilazodone	In-Vitro Only
118	2C19	voriconazole	Strong inhibitor
119	2D6	zuclopenthixol	In-Vitro Only

will decrease ticlopidine effect

#

enzyme

inducers

ticlopidine will not affect

Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.