The following drugs will decrease sulfamethoxazole effect

#

enzyme

inducers

the follwing drugs will Increase sulfamethoxazole effect

#

enzyme

Inhibitors

level

The follwing drugs will Increase effect by sulfamethoxazole effect

#	enzyme	drug	level
1	2C9	amitriptyline	Weak inhibitor
2	2C9	azilsartan	Weak inhibitor
3	2C9	capecitabine	Weak inhibitor
4	2C9	celecoxib	Weak inhibitor
5	2C9	clopidogrel	Weak inhibitor
6	2C9	diclofenac	Weak inhibitor
7	2C9	doxepin	Weak inhibitor
8	2C9	fluoxetine	Weak inhibitor
9	2C9	fluvastatin	Weak inhibitor
10	2C9	glibenclamide	Weak inhibitor
11	2C9	glimepiride	Weak inhibitor
12	2C9	glipizide	Weak inhibitor
13	2C9	glyburide	Weak inhibitor
14	2C9	ibuprofen	Weak inhibitor
15	2C9	irbesartan	Weak inhibitor
16	2C9	lesinurad	Weak inhibitor
17	2C9	lornoxicam	Weak inhibitor
18	2C9	losartan	Weak inhibitor
19	2C9	meloxicam	Weak inhibitor
20	2C9	nateglinide	Weak inhibitor
21	2C9	olodaterol	Weak inhibitor
22	2C9	ospemifene	Weak inhibitor
23	2C9	phenytoin	Weak inhibitor
24	2C9	piroxicam	Weak inhibitor
25	2C9	rosiglitazone	Weak inhibitor
26	2C9	s-warfarin	Weak inhibitor
27	2C9	suprofen	Weak inhibitor
28	2C9	tamoxifen	Weak inhibitor
29	2C9	tolbutamide	Weak inhibitor
30	2C9	torsemide	Weak inhibitor
31	2C9	valproic acid	Weak inhibitor
32	2C9	venlafaxine	Weak inhibitor
33	2C9	voriconazole	Weak inhibitor
34	2C9	zafirlukast	Weak inhibitor

will decrease sulfamethoxazole effect

#

enzyme

inducers

sulfamethoxazole will not affect

Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.