The following drugs will decrease oral contraceptives effect

#

enzyme

inducers

the follwing drugs will Increase oral contraceptives effect

#

enzyme

Inhibitors

level

The follwing drugs will Increase effect by oral contraceptives effect

#	enzyme	drug	level
1	2C19	amitriptyline	Weak inhibitor
2	2C19	atomoxetine	Weak inhibitor
3	2C19	brivaracetam	Weak inhibitor
4	2C19	carisoprodol	Weak inhibitor
5	2C19	celecoxib	Weak inhibitor
6	2C19	chloramphenicol	Weak inhibitor
7	2C19	citalopram	Weak inhibitor
8	2C19	clobazam	Weak inhibitor
9	2C19	clomipramine	Weak inhibitor
10	2C19	clopidogrel	Weak inhibitor
11	2C19	cyclophosphamide	Weak inhibitor
12	2C19	diazepam	Weak inhibitor
13	2C19	doxepin	Weak inhibitor
14	2C19	escitalopram	Weak inhibitor
15	2C19	esomeprazole	Weak inhibitor
16	2C19	flibanserin	Weak inhibitor
17	2C19	hexobarbital	Weak inhibitor
18	2C19	imipramine	Weak inhibitor
19	2C19	indomethacin	Weak inhibitor
20	2C19	labetalol	Weak inhibitor
21	2C19	lansoprazole	Weak inhibitor
22	2C19	mavacamten	Weak inhibitor
23	2C19	moclobemide	Weak inhibitor
24	2C19	nelfinavir	Weak inhibitor
25	2C19	nilutamide	Weak inhibitor
26	2C19	omeprazole	Weak inhibitor
27	2C19	ospemifene	Weak inhibitor
28	2C19	pantoprazole	Weak inhibitor
29	2C19	phenobarbitone	Weak inhibitor
30	2C19	phenytoin	Weak inhibitor
31	2C19	pomalidomide	Weak inhibitor
32	2C19	primidone	Weak inhibitor
33	2C19	progesterone	Weak inhibitor
34	2C19	proguanil	Weak inhibitor
35	2C19	propranolol	Weak inhibitor
36	2C19	r-mephobarbital	Weak inhibitor
37	2C19	r-warfarin	Weak inhibitor
38	2C19	s-mephenytoin	Weak inhibitor
39	2C19	suvorexant	Weak inhibitor
40	2C19	teniposide	Weak inhibitor
41	2C19	tofacitinib	Weak inhibitor
42	2C19	venlafaxine	Weak inhibitor
43	2C19	vilazodone	Weak inhibitor
44	2C19	voriconazole	Weak inhibitor

will decrease oral contraceptives effect

#

enzyme

inducers

oral contraceptives will not affect

Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.