midodrine
The following drugs will decrease midodrine effect
the follwing drugs will
Increase midodrine effect
The follwing drugs will Increase effect by midodrine effect
# | enzyme | drug | level |
1 | 2D6 | alprenolol | |
2 | 2D6 | amitriptyline | |
3 | 2D6 | amphetamine | |
4 | 2D6 | atomoxetine | |
5 | 2D6 | brexpiprazole | |
6 | 2D6 | bufuralol | |
7 | 2D6 | cariprazine | |
8 | 2D6 | carvedilol | |
9 | 2D6 | chlorpheniramine | |
10 | 2D6 | chlorpromazine | |
11 | 2D6 | citalopram | |
12 | 2D6 | clomipramine | |
13 | 2D6 | clonidine | |
14 | 2D6 | codeine | |
15 | 2D6 | debrisoquine | |
16 | 2D6 | desipramine | |
17 | 2D6 | deutetrabenazine | |
18 | 2D6 | dexfenfluramine | |
19 | 2D6 | dextromethorphan | |
20 | 2D6 | donepezil | |
21 | 2D6 | doxepin | |
22 | 2D6 | eliglustat | |
23 | 2D6 | encainide | |
24 | 2D6 | escitalopram | |
25 | 2D6 | flecainide | |
26 | 2D6 | fluoxetine | |
27 | 2D6 | fluvoxamine | |
28 | 2D6 | ibrutinib | |
29 | 2D6 | imipramine | |
30 | 2D6 | lidocaine | |
31 | 2D6 | metoclopramide | |
32 | 2D6 | metoprolol | |
33 | 2D6 | mexiletine | |
34 | 2D6 | minaprine | |
35 | 2D6 | nebivolol | |
36 | 2D6 | nortriptyline | |
37 | 2D6 | ondansetron | |
38 | 2D6 | oxycodone | |
39 | 2D6 | paroxetine | |
40 | 2D6 | perhexiline | |
41 | 2D6 | perphenazine | |
42 | 2D6 | phenacetin | |
43 | 2D6 | pimavanserin | |
44 | 2D6 | ponatinib | |
45 | 2D6 | promethazine | |
46 | 2D6 | propafenone | |
47 | 2D6 | propranolol | |
48 | 2D6 | risperidone | |
49 | 2D6 | rucaparib | |
50 | 2D6 | sparteine | |
51 | 2D6 | tamoxifen | |
52 | 2D6 | tetrabenzine | |
53 | 2D6 | thioridazine | |
54 | 2D6 | timolol | |
55 | 2D6 | tramadol | |
56 | 2D6 | umeclidinium | |
57 | 2D6 | valbenazine | |
58 | 2D6 | venlafaxine | |
59 | 2D6 | vilazodone | |
60 | 2D6 | zuclopenthixol | |
will
decrease midodrine effect
midodrine will not affect
Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.