hydroxyzine
The following drugs will decrease hydroxyzine effect
the follwing drugs will
Increase hydroxyzine effect
The follwing drugs will Increase effect by hydroxyzine effect
| # | enzyme | drug | level |
| 1 | 2D6 | alprenolol | In-Vitro Only |
| 2 | 2D6 | amitriptyline | In-Vitro Only |
| 3 | 2D6 | amphetamine | In-Vitro Only |
| 4 | 2D6 | atomoxetine | In-Vitro Only |
| 5 | 2D6 | brexpiprazole | In-Vitro Only |
| 6 | 2D6 | bufuralol | In-Vitro Only |
| 7 | 2D6 | cariprazine | In-Vitro Only |
| 8 | 2D6 | carvedilol | In-Vitro Only |
| 9 | 2D6 | chlorpheniramine | In-Vitro Only |
| 10 | 2D6 | chlorpromazine | In-Vitro Only |
| 11 | 2D6 | citalopram | In-Vitro Only |
| 12 | 2D6 | clomipramine | In-Vitro Only |
| 13 | 2D6 | clonidine | In-Vitro Only |
| 14 | 2D6 | codeine | In-Vitro Only |
| 15 | 2D6 | debrisoquine | In-Vitro Only |
| 16 | 2D6 | desipramine | In-Vitro Only |
| 17 | 2D6 | deutetrabenazine | In-Vitro Only |
| 18 | 2D6 | dexfenfluramine | In-Vitro Only |
| 19 | 2D6 | dextromethorphan | In-Vitro Only |
| 20 | 2D6 | donepezil | In-Vitro Only |
| 21 | 2D6 | doxepin | In-Vitro Only |
| 22 | 2D6 | eliglustat | In-Vitro Only |
| 23 | 2D6 | encainide | In-Vitro Only |
| 24 | 2D6 | escitalopram | In-Vitro Only |
| 25 | 2D6 | flecainide | In-Vitro Only |
| 26 | 2D6 | fluoxetine | In-Vitro Only |
| 27 | 2D6 | fluvoxamine | In-Vitro Only |
| 28 | 2D6 | ibrutinib | In-Vitro Only |
| 29 | 2D6 | imipramine | In-Vitro Only |
| 30 | 2D6 | lidocaine | In-Vitro Only |
| 31 | 2D6 | metoclopramide | In-Vitro Only |
| 32 | 2D6 | metoprolol | In-Vitro Only |
| 33 | 2D6 | mexiletine | In-Vitro Only |
| 34 | 2D6 | minaprine | In-Vitro Only |
| 35 | 2D6 | nebivolol | In-Vitro Only |
| 36 | 2D6 | nortriptyline | In-Vitro Only |
| 37 | 2D6 | ondansetron | In-Vitro Only |
| 38 | 2D6 | oxycodone | In-Vitro Only |
| 39 | 2D6 | paroxetine | In-Vitro Only |
| 40 | 2D6 | perhexiline | In-Vitro Only |
| 41 | 2D6 | perphenazine | In-Vitro Only |
| 42 | 2D6 | phenacetin | In-Vitro Only |
| 43 | 2D6 | pimavanserin | In-Vitro Only |
| 44 | 2D6 | ponatinib | In-Vitro Only |
| 45 | 2D6 | promethazine | In-Vitro Only |
| 46 | 2D6 | propafenone | In-Vitro Only |
| 47 | 2D6 | propranolol | In-Vitro Only |
| 48 | 2D6 | risperidone | In-Vitro Only |
| 49 | 2D6 | rucaparib | In-Vitro Only |
| 50 | 2D6 | sparteine | In-Vitro Only |
| 51 | 2D6 | tamoxifen | In-Vitro Only |
| 52 | 2D6 | tetrabenzine | In-Vitro Only |
| 53 | 2D6 | thioridazine | In-Vitro Only |
| 54 | 2D6 | timolol | In-Vitro Only |
| 55 | 2D6 | tramadol | In-Vitro Only |
| 56 | 2D6 | umeclidinium | In-Vitro Only |
| 57 | 2D6 | valbenazine | In-Vitro Only |
| 58 | 2D6 | venlafaxine | In-Vitro Only |
| 59 | 2D6 | vilazodone | In-Vitro Only |
| 60 | 2D6 | zuclopenthixol | In-Vitro Only |
will
decrease hydroxyzine effect
hydroxyzine will not affect
Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.