felbamate
The following drugs will decrease felbamate effect
the follwing drugs will
Increase felbamate effect
The follwing drugs will Increase effect by felbamate effect
# | enzyme | drug | level |
1 | 2C19 | amitriptyline | Weak inhibitor |
2 | 2C19 | atomoxetine | Weak inhibitor |
3 | 2C19 | brivaracetam | Weak inhibitor |
4 | 2C19 | carisoprodol | Weak inhibitor |
5 | 2C19 | celecoxib | Weak inhibitor |
6 | 2C19 | chloramphenicol | Weak inhibitor |
7 | 2C19 | citalopram | Weak inhibitor |
8 | 2C19 | clobazam | Weak inhibitor |
9 | 2C19 | clomipramine | Weak inhibitor |
10 | 2C19 | clopidogrel | Weak inhibitor |
11 | 2C19 | cyclophosphamide | Weak inhibitor |
12 | 2C19 | diazepam | Weak inhibitor |
13 | 2C19 | doxepin | Weak inhibitor |
14 | 2C19 | escitalopram | Weak inhibitor |
15 | 2C19 | esomeprazole | Weak inhibitor |
16 | 2C19 | flibanserin | Weak inhibitor |
17 | 2C19 | hexobarbital | Weak inhibitor |
18 | 2C19 | imipramine | Weak inhibitor |
19 | 2C19 | indomethacin | Weak inhibitor |
20 | 2C19 | labetalol | Weak inhibitor |
21 | 2C19 | lansoprazole | Weak inhibitor |
22 | 2C19 | mavacamten | Weak inhibitor |
23 | 2C19 | moclobemide | Weak inhibitor |
24 | 2C19 | nelfinavir | Weak inhibitor |
25 | 2C19 | nilutamide | Weak inhibitor |
26 | 2C19 | omeprazole | Weak inhibitor |
27 | 2C19 | ospemifene | Weak inhibitor |
28 | 2C19 | pantoprazole | Weak inhibitor |
29 | 2C19 | phenobarbitone | Weak inhibitor |
30 | 2C19 | phenytoin | Weak inhibitor |
31 | 2C19 | pomalidomide | Weak inhibitor |
32 | 2C19 | primidone | Weak inhibitor |
33 | 2C19 | progesterone | Weak inhibitor |
34 | 2C19 | proguanil | Weak inhibitor |
35 | 2C19 | propranolol | Weak inhibitor |
36 | 2C19 | r-mephobarbital | Weak inhibitor |
37 | 2C19 | r-warfarin | Weak inhibitor |
38 | 2C19 | s-mephenytoin | Weak inhibitor |
39 | 2C19 | suvorexant | Weak inhibitor |
40 | 2C19 | teniposide | Weak inhibitor |
41 | 2C19 | tofacitinib | Weak inhibitor |
42 | 2C19 | venlafaxine | Weak inhibitor |
43 | 2C19 | vilazodone | Weak inhibitor |
44 | 2C19 | voriconazole | Weak inhibitor |
will
decrease felbamate effect
felbamate will not affect
Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.