The following drugs will decrease escitalopram effect

#	enzyme	inducers
0	3A457	barbiturates
1	3A457	brigatinib
2	2C19	carbamazepine
3	3A457	carbamazepine
4	3A457	clobazam
5	3A457	dabrafenib
6	2C19	efavirenz
7	3A457	efavirenz
8	2C19	enzalutamide
9	3A457	elagolix
10	3A457	enzalutamide
11	2C19	letermovir
12	3A457	eslicarbazepine
13	3A457	glucocorticoids
14	3A457	letermovir
15	3A457	lorlatinib
16	3A457	modafinil
17	3A457	nevirapine
18	3A457	oxcarbazepine
19	2C19	norethindrone
20	3A457	perampanel
21	2C19	prednisone
22	2C19	rifampicin
23	3A457	phenobarbital
24	2C19	ritonavir
25	3A457	phenytoin
26	3A457	pioglitazone
27	3A457	rifabutin
28	3A457	rifampin
29	3A457	St. John's Wort
30	3A457	telotristat
31	3A457	troglitazone
32	3A457	vemurafenib

the follwing drugs will Increase escitalopram effect

#	enzyme	Inhibitors	level
0	2D6	abiraterone	Moderate inhibitor
1	2D6	amiodarone	Weak inhibitor
2	3A457	amiodarone	under review
3	3A457	aprepitant	Moderate inhibitor
4	2C19	armodafinil	Weak inhibitor
5	3A457	atomoxetine
6	3A457	boceprevir	under review
7	2D6	bupropion	Strong inhibitor
8	2D6	celecoxib	Weak inhibitor
9	3A457	ceritinib	Strong inhibitor
10	2C19	chloramphenicol	In-Vitro Only
11	3A457	chloramphenicol	In-Vitro Only
12	2D6	chlorpromazine	In-Vitro Only
13	2C19	cimetidine	Weak inhibitor
14	2D6	cimetidine	Weak inhibitor
15	3A457	cimetidine
16	2D6	cinacalcet	Moderate inhibitor
17	3A457	ciprofloxacin	under review
18	2C19	citalopram	Weak inhibitor
19	2D6	citalopram	Weak inhibitor
20	3A457	clarithromycin	Strong inhibitor
21	2D6	clemastine	In-Vitro Only
22	2D6	clobazam
23	2D6	clomipramine
24	2D6	cocaine	In-Vitro Only
25	3A457	crizotinib	Moderate inhibitor
26	3A457	delaviridine	under review
27	3A457	diethyl-dithiocarbamate
28	3A457	diltiazem	Moderate inhibitor
29	2D6	diphenhydramine
30	2D6	doxepin	Moderate inhibitor
31	2D6	duloxetine	Moderate inhibitor
32	3A457	entrectinib
33	3A457	erythromycin	Moderate inhibitor
34	2D6	escitalopram
35	2C19	esomeprazole	Weak inhibitor
36	3A457	esomeprazole
37	2C19	felbamate	Weak inhibitor
38	2C19	fluconazole	Moderate inhibitor
39	3A457	fluconazole	Moderate inhibitor
40	2C19	fluoxetine	Moderate inhibitor
41	2D6	fluoxetine	Strong inhibitor
42	2C19	fluvoxamine	Strong inhibitor
43	3A457	fluvoxamine	under review
44	3A457	gestodene	under review
45	3A457	grapefruit juice	Moderate inhibitor
46	2D6	halofantrine	Moderate inhibitor
47	2D6	haloperidol	In-Vitro Only
48	2D6	hydroxyzine	In-Vitro Only
49	3A457	idelalisib	Strong inhibitor
50	3A457	imatinib	under review
51	3A457	indinavir	Strong inhibitor
52	2C19	isoniazid	Weak inhibitor
53	3A457	itraconazole	Strong inhibitor
54	3A457	ivacaftor
55	2C19	ketoconazole	Moderate inhibitor
56	3A457	ketoconazole	Strong inhibitor
57	3A457	lesinurad
58	3A457	letermovir
59	2D6	levomepromazine
60	2D6	lorcaserin	Moderate inhibitor
61	2C19	luliconazole	Weak inhibitor
62	2D6	methadone	under review
63	2D6	metoclopramide	In-Vitro Only
64	3A457	mibefradil	Strong inhibitor
65	2D6	midodrine
66	3A457	mifepristone	under review
67	2D6	moclobemide	Moderate inhibitor
68	2C19	modafinil	Weak inhibitor
69	3A457	nefazodone	Strong inhibitor
70	3A457	nelfinavir	Strong inhibitor
71	3A457	netupitant/palonosetron	Moderate inhibitor
72	3A457	norfloxacin	under review
73	3A457	norfluoxetine	under review
74	2C19	omeprazole	Weak inhibitor
75	3A457	omeprazole	Weak inhibitor
76	2C19	oral contraceptives	Weak inhibitor
77	2C19	oritavancin	In-Vitro Only
78	2D6	panobinostat	under review
79	2C19	pantoprazole	Weak inhibitor
80	3A457	pantoprazole
81	2D6	paroxetine	Strong inhibitor
82	3A457	perampanel
83	2D6	perphenazine	In-Vitro Only
84	2D6	promethazine	under review
85	2C19	quercetin	In-Vitro Only
86	3A457	quercetin
87	2D6	quinidine	Strong inhibitor
88	3A457	regorafenib	under review
89	3A457	ribociclib	Strong inhibitor
90	2D6	ritonavir
91	3A457	ritonavir	Strong inhibitor
92	2D6	rolapitant	Moderate inhibitor
93	3A457	rucaparib
94	3A457	saquinavir	Strong inhibitor
95	2D6	sertraline
96	3A457	simeprevir
97	3A457	starfruit	under review
98	3A457	telaprevir	under review
99	3A457	telithromycin	Strong inhibitor
100	2D6	terbinafine (oral)	Moderate inhibitor
101	3A457	ticagrelor
102	2C19	ticlopidine	Strong inhibitor
103	2D6	ticlopidine	In-Vitro Only
104	2C19	topiramate	under review
105	2D6	tripelennamine	In-Vitro Only
106	3A457	tucatinib	Strong inhibitor
107	2D6	vemurafenib
108	3A457	verapamil	Moderate inhibitor
109	2C19	voriconazole	Moderate inhibitor
110	3A457	voriconazole	Strong inhibitor

The follwing drugs will Increase effect by escitalopram effect

#	enzyme	drug	level
1	2D6	alprenolol
2	2D6	amitriptyline
3	2D6	amphetamine
4	2D6	atomoxetine
5	2D6	brexpiprazole
6	2D6	bufuralol
7	2D6	cariprazine
8	2D6	carvedilol
9	2D6	chlorpheniramine
10	2D6	chlorpromazine
11	2D6	citalopram
12	2D6	clomipramine
13	2D6	clonidine
14	2D6	codeine
15	2D6	debrisoquine
16	2D6	desipramine
17	2D6	deutetrabenazine
18	2D6	dexfenfluramine
19	2D6	dextromethorphan
20	2D6	donepezil
21	2D6	doxepin
22	2D6	eliglustat
23	2D6	encainide
24	2D6	escitalopram
25	2D6	flecainide
26	2D6	fluoxetine
27	2D6	fluvoxamine
28	2D6	ibrutinib
29	2D6	imipramine
30	2D6	lidocaine
31	2D6	metoclopramide
32	2D6	metoprolol
33	2D6	mexiletine
34	2D6	minaprine
35	2D6	nebivolol
36	2D6	nortriptyline
37	2D6	ondansetron
38	2D6	oxycodone
39	2D6	paroxetine
40	2D6	perhexiline
41	2D6	perphenazine
42	2D6	phenacetin
43	2D6	pimavanserin
44	2D6	ponatinib
45	2D6	promethazine
46	2D6	propafenone
47	2D6	propranolol
48	2D6	risperidone
49	2D6	rucaparib
50	2D6	sparteine
51	2D6	tamoxifen
52	2D6	tetrabenzine
53	2D6	thioridazine
54	2D6	timolol
55	2D6	tramadol
56	2D6	umeclidinium
57	2D6	valbenazine
58	2D6	venlafaxine
59	2D6	vilazodone
60	2D6	zuclopenthixol

will decrease escitalopram effect

#

enzyme

inducers

escitalopram will not affect

Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.