citalopram
The following drugs will decrease citalopram effect
# | enzyme | inducers |
0 | 3A457 | barbiturates |
1 | 3A457 | brigatinib |
2 | 2C19 | carbamazepine |
3 | 3A457 | carbamazepine |
4 | 3A457 | clobazam |
5 | 3A457 | dabrafenib |
6 | 2C19 | efavirenz |
7 | 3A457 | efavirenz |
8 | 2C19 | enzalutamide |
9 | 3A457 | elagolix |
10 | 3A457 | enzalutamide |
11 | 3A457 | eslicarbazepine |
12 | 3A457 | glucocorticoids |
13 | 3A457 | letermovir |
14 | 3A457 | lorlatinib |
15 | 3A457 | modafinil |
16 | 3A457 | nevirapine |
17 | 3A457 | oxcarbazepine |
18 | 2C19 | norethindrone |
19 | 3A457 | perampanel |
20 | 2C19 | prednisone |
21 | 2C19 | rifampicin |
22 | 3A457 | phenobarbital |
23 | 2C19 | ritonavir |
24 | 3A457 | phenytoin |
25 | 3A457 | pioglitazone |
26 | 3A457 | rifabutin |
27 | 3A457 | rifampin |
28 | 3A457 | St. John's Wort |
29 | 3A457 | telotristat |
30 | 3A457 | troglitazone |
31 | 3A457 | vemurafenib |
the follwing drugs will
Increase citalopram effect
# | enzyme | Inhibitors | level |
0 | 2D6 | abiraterone | Moderate inhibitor |
1 | 2D6 | amiodarone | Weak inhibitor |
2 | 3A457 | amiodarone | under review |
3 | 3A457 | aprepitant | Moderate inhibitor |
4 | 2C19 | armodafinil | Weak inhibitor |
5 | 3A457 | atomoxetine | |
6 | 3A457 | boceprevir | under review |
7 | 2D6 | bupropion | Strong inhibitor |
8 | 2D6 | celecoxib | Weak inhibitor |
9 | 3A457 | ceritinib | Strong inhibitor |
10 | 2C19 | chloramphenicol | In-Vitro Only |
11 | 3A457 | chloramphenicol | In-Vitro Only |
12 | 2D6 | chlorpromazine | In-Vitro Only |
13 | 2C19 | cimetidine | Weak inhibitor |
14 | 2D6 | cimetidine | Weak inhibitor |
15 | 3A457 | cimetidine | |
16 | 2D6 | cinacalcet | Moderate inhibitor |
17 | 3A457 | ciprofloxacin | under review |
18 | 2D6 | citalopram | Weak inhibitor |
19 | 3A457 | clarithromycin | Strong inhibitor |
20 | 2D6 | clemastine | In-Vitro Only |
21 | 2D6 | clobazam | |
22 | 2D6 | clomipramine | |
23 | 2D6 | cocaine | In-Vitro Only |
24 | 3A457 | crizotinib | Moderate inhibitor |
25 | 3A457 | delaviridine | under review |
26 | 3A457 | diethyl-dithiocarbamate | |
27 | 3A457 | diltiazem | Moderate inhibitor |
28 | 2D6 | diphenhydramine | |
29 | 2D6 | doxepin | Moderate inhibitor |
30 | 2D6 | duloxetine | Moderate inhibitor |
31 | 3A457 | entrectinib | |
32 | 3A457 | erythromycin | Moderate inhibitor |
33 | 2D6 | escitalopram | |
34 | 2C19 | esomeprazole | Weak inhibitor |
35 | 3A457 | esomeprazole | |
36 | 2C19 | felbamate | Weak inhibitor |
37 | 2C19 | fluconazole | Moderate inhibitor |
38 | 3A457 | fluconazole | Moderate inhibitor |
39 | 2C19 | fluoxetine | Moderate inhibitor |
40 | 2D6 | fluoxetine | Strong inhibitor |
41 | 2C19 | fluvoxamine | Strong inhibitor |
42 | 3A457 | fluvoxamine | under review |
43 | 3A457 | gestodene | under review |
44 | 3A457 | grapefruit juice | Moderate inhibitor |
45 | 2D6 | halofantrine | Moderate inhibitor |
46 | 2D6 | haloperidol | In-Vitro Only |
47 | 2D6 | hydroxyzine | In-Vitro Only |
48 | 3A457 | idelalisib | Strong inhibitor |
49 | 3A457 | imatinib | under review |
50 | 3A457 | indinavir | Strong inhibitor |
51 | 2C19 | isoniazid | Weak inhibitor |
52 | 3A457 | itraconazole | Strong inhibitor |
53 | 3A457 | ivacaftor | |
54 | 2C19 | ketoconazole | Moderate inhibitor |
55 | 3A457 | ketoconazole | Strong inhibitor |
56 | 3A457 | lesinurad | |
57 | 3A457 | letermovir | |
58 | 2D6 | levomepromazine | |
59 | 2D6 | lorcaserin | Moderate inhibitor |
60 | 2C19 | luliconazole | Weak inhibitor |
61 | 2D6 | methadone | under review |
62 | 2D6 | metoclopramide | In-Vitro Only |
63 | 3A457 | mibefradil | Strong inhibitor |
64 | 2D6 | midodrine | |
65 | 3A457 | mifepristone | under review |
66 | 2D6 | moclobemide | Moderate inhibitor |
67 | 2C19 | modafinil | Weak inhibitor |
68 | 3A457 | nefazodone | Strong inhibitor |
69 | 3A457 | nelfinavir | Strong inhibitor |
70 | 3A457 | netupitant/palonosetron | Moderate inhibitor |
71 | 3A457 | norfloxacin | under review |
72 | 3A457 | norfluoxetine | under review |
73 | 2C19 | omeprazole | Weak inhibitor |
74 | 3A457 | omeprazole | Weak inhibitor |
75 | 2C19 | oral contraceptives | Weak inhibitor |
76 | 2C19 | oritavancin | In-Vitro Only |
77 | 2D6 | panobinostat | under review |
78 | 2C19 | pantoprazole | Weak inhibitor |
79 | 3A457 | pantoprazole | |
80 | 2D6 | paroxetine | Strong inhibitor |
81 | 3A457 | perampanel | |
82 | 2D6 | perphenazine | In-Vitro Only |
83 | 2D6 | promethazine | under review |
84 | 2C19 | quercetin | In-Vitro Only |
85 | 3A457 | quercetin | |
86 | 2D6 | quinidine | Strong inhibitor |
87 | 3A457 | regorafenib | under review |
88 | 3A457 | ribociclib | Strong inhibitor |
89 | 2D6 | ritonavir | |
90 | 3A457 | ritonavir | Strong inhibitor |
91 | 2D6 | rolapitant | Moderate inhibitor |
92 | 3A457 | rucaparib | |
93 | 3A457 | saquinavir | Strong inhibitor |
94 | 2D6 | sertraline | |
95 | 3A457 | simeprevir | |
96 | 3A457 | starfruit | under review |
97 | 3A457 | telaprevir | under review |
98 | 3A457 | telithromycin | Strong inhibitor |
99 | 2D6 | terbinafine (oral) | Moderate inhibitor |
100 | 3A457 | ticagrelor | |
101 | 2C19 | ticlopidine | Strong inhibitor |
102 | 2D6 | ticlopidine | In-Vitro Only |
103 | 2C19 | topiramate | under review |
104 | 2D6 | tripelennamine | In-Vitro Only |
105 | 3A457 | tucatinib | Strong inhibitor |
106 | 2D6 | vemurafenib | |
107 | 3A457 | verapamil | Moderate inhibitor |
108 | 2C19 | voriconazole | Moderate inhibitor |
109 | 3A457 | voriconazole | Strong inhibitor |
The follwing drugs will Increase effect by citalopram effect
# | enzyme | drug | level |
1 | 1A2 | acetaminophen | Weak inhibitor |
2 | 2D6 | alprenolol | Weak inhibitor |
3 | 2D6 | amitriptyline | Weak inhibitor |
4 | 1A2 | amitriptyline | Weak inhibitor |
5 | 2C19 | amitriptyline | Weak inhibitor |
6 | 2D6 | amphetamine | Weak inhibitor |
7 | 1A2 | apremilast | Weak inhibitor |
8 | 2D6 | atomoxetine | Weak inhibitor |
9 | 2C19 | atomoxetine | Weak inhibitor |
10 | 2D6 | brexpiprazole | Weak inhibitor |
11 | 2C19 | brivaracetam | Weak inhibitor |
12 | 2D6 | bufuralol | Weak inhibitor |
13 | 1A2 | caffeine | Weak inhibitor |
14 | 2D6 | cariprazine | Weak inhibitor |
15 | 2C19 | carisoprodol | Weak inhibitor |
16 | 2D6 | carvedilol | Weak inhibitor |
17 | 2C19 | celecoxib | Weak inhibitor |
18 | 2C19 | chloramphenicol | Weak inhibitor |
19 | 2D6 | chlorpheniramine | Weak inhibitor |
20 | 2D6 | chlorpromazine | Weak inhibitor |
21 | 2D6 | citalopram | Weak inhibitor |
22 | 2C19 | clobazam | Weak inhibitor |
23 | 2D6 | clomipramine | Weak inhibitor |
24 | 1A2 | clomipramine | Weak inhibitor |
25 | 2C19 | clomipramine | Weak inhibitor |
26 | 2D6 | clonidine | Weak inhibitor |
27 | 2C19 | clopidogrel | Weak inhibitor |
28 | 1A2 | clozapine | Weak inhibitor |
29 | 2D6 | codeine | Weak inhibitor |
30 | 1A2 | cyclobenzaprine | Weak inhibitor |
31 | 2C19 | cyclophosphamide | Weak inhibitor |
32 | 2D6 | debrisoquine | Weak inhibitor |
33 | 2D6 | desipramine | Weak inhibitor |
34 | 2D6 | deutetrabenazine | Weak inhibitor |
35 | 2D6 | dexfenfluramine | Weak inhibitor |
36 | 2D6 | dextromethorphan | Weak inhibitor |
37 | 2C19 | diazepam | Weak inhibitor |
38 | 2D6 | donepezil | Weak inhibitor |
39 | 2D6 | doxepin | Weak inhibitor |
40 | 1A2 | doxepin | Weak inhibitor |
41 | 2C19 | doxepin | Weak inhibitor |
42 | 1A2 | duloxetine | Weak inhibitor |
43 | 2D6 | eliglustat | Weak inhibitor |
44 | 2D6 | encainide | Weak inhibitor |
45 | 2D6 | escitalopram | Weak inhibitor |
46 | 2C19 | escitalopram | Weak inhibitor |
47 | 2C19 | esomeprazole | Weak inhibitor |
48 | 1A2 | estradiol | Weak inhibitor |
49 | 2D6 | flecainide | Weak inhibitor |
50 | 2C19 | flibanserin | Weak inhibitor |
51 | 2D6 | fluoxetine | Weak inhibitor |
52 | 2D6 | fluvoxamine | Weak inhibitor |
53 | 1A2 | fluvoxamine | Weak inhibitor |
54 | 1A2 | haloperidol | Weak inhibitor |
55 | 2C19 | hexobarbital | Weak inhibitor |
56 | 2D6 | ibrutinib | Weak inhibitor |
57 | 2D6 | imipramine | Weak inhibitor |
58 | 1A2 | imipramine | Weak inhibitor |
59 | 2C19 | imipramine | Weak inhibitor |
60 | 2C19 | indomethacin | Weak inhibitor |
61 | 2C19 | labetalol | Weak inhibitor |
62 | 2C19 | lansoprazole | Weak inhibitor |
63 | 2D6 | lidocaine | Weak inhibitor |
64 | 2C19 | mavacamten | Weak inhibitor |
65 | 2D6 | metoclopramide | Weak inhibitor |
66 | 2D6 | metoprolol | Weak inhibitor |
67 | 2D6 | mexiletine | Weak inhibitor |
68 | 1A2 | mexiletine | Weak inhibitor |
69 | 2D6 | minaprine | Weak inhibitor |
70 | 2C19 | moclobemide | Weak inhibitor |
71 | 1A2 | nabumetone | Weak inhibitor |
72 | 1A2 | naproxen | Weak inhibitor |
73 | 2D6 | nebivolol | Weak inhibitor |
74 | 2C19 | nelfinavir | Weak inhibitor |
75 | 2C19 | nilutamide | Weak inhibitor |
76 | 2D6 | nortriptyline | Weak inhibitor |
77 | 1A2 | olanzapine | Weak inhibitor |
78 | 2C19 | omeprazole | Weak inhibitor |
79 | 2D6 | ondansetron | Weak inhibitor |
80 | 1A2 | ondansetron | Weak inhibitor |
81 | 2C19 | ospemifene | Weak inhibitor |
82 | 2D6 | oxycodone | Weak inhibitor |
83 | 2C19 | pantoprazole | Weak inhibitor |
84 | 2D6 | paroxetine | Weak inhibitor |
85 | 2D6 | perhexiline | Weak inhibitor |
86 | 2D6 | perphenazine | Weak inhibitor |
87 | 2D6 | phenacetin | Weak inhibitor |
88 | 1A2 | phenacetin | Weak inhibitor |
89 | 2C19 | phenobarbitone | Weak inhibitor |
90 | 2C19 | phenytoin | Weak inhibitor |
91 | 2D6 | pimavanserin | Weak inhibitor |
92 | 1A2 | pirfenidone | Weak inhibitor |
93 | 1A2 | pomalidomide | Weak inhibitor |
94 | 2C19 | pomalidomide | Weak inhibitor |
95 | 2D6 | ponatinib | Weak inhibitor |
96 | 2C19 | primidone | Weak inhibitor |
97 | 2C19 | progesterone | Weak inhibitor |
98 | 2C19 | proguanil | Weak inhibitor |
99 | 2D6 | promethazine | Weak inhibitor |
100 | 2D6 | propafenone | Weak inhibitor |
101 | 2D6 | propranolol | Weak inhibitor |
102 | 1A2 | propranolol | Weak inhibitor |
103 | 2C19 | propranolol | Weak inhibitor |
104 | 2C19 | r-mephobarbital | Weak inhibitor |
105 | 2C19 | r-warfarin | Weak inhibitor |
106 | 1A2 | riluzole | Weak inhibitor |
107 | 2D6 | risperidone | Weak inhibitor |
108 | 1A2 | roflumilast | Weak inhibitor |
109 | 1A2 | ropivacaine | Weak inhibitor |
110 | 2D6 | rucaparib | Weak inhibitor |
111 | 1A2 | rucaparib | Weak inhibitor |
112 | 2C19 | s-mephenytoin | Weak inhibitor |
113 | 2D6 | sparteine | Weak inhibitor |
114 | 2C19 | suvorexant | Weak inhibitor |
115 | 1A2 | tacrine | Weak inhibitor |
116 | 2D6 | tamoxifen | Weak inhibitor |
117 | 1A2 | tasimelteon | Weak inhibitor |
118 | 2C19 | teniposide | Weak inhibitor |
119 | 2D6 | tetrabenzine | Weak inhibitor |
120 | 1A2 | theophylline | Weak inhibitor |
121 | 2D6 | thioridazine | Weak inhibitor |
122 | 2D6 | timolol | Weak inhibitor |
123 | 1A2 | tizanidine | Weak inhibitor |
124 | 2C19 | tofacitinib | Weak inhibitor |
125 | 2D6 | tramadol | Weak inhibitor |
126 | 1A2 | triamterene | Weak inhibitor |
127 | 2D6 | umeclidinium | Weak inhibitor |
128 | 2D6 | valbenazine | Weak inhibitor |
129 | 2D6 | venlafaxine | Weak inhibitor |
130 | 2C19 | venlafaxine | Weak inhibitor |
131 | 1A2 | verapamil | Weak inhibitor |
132 | 2D6 | vilazodone | Weak inhibitor |
133 | 2C19 | vilazodone | Weak inhibitor |
134 | 2C19 | voriconazole | Weak inhibitor |
135 | 1A2 | warfarin | Weak inhibitor |
136 | 1A2 | zileuton | Weak inhibitor |
137 | 1A2 | zolmitriptan | Weak inhibitor |
138 | 2D6 | zuclopenthixol | Weak inhibitor |
will
decrease citalopram effect
citalopram will not affect
Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.