The following drugs will decrease celecoxib effect

#	enzyme	inducers
0	2C9	carbamazepine
1	2C19	carbamazepine
2	2C9	dabrafenib
3	2C9	enzalutamide
4	2C19	efavirenz
5	2C19	enzalutamide
6	2C19	letermovir
7	2C9	letermovir
8	2C19	norethindrone
9	2C19	prednisone
10	2C9	nevirapine
11	2C9	phenobarbital
12	2C19	rifampicin
13	2C19	ritonavir
14	2C9	rifampin
15	2C9	secobarbital

the follwing drugs will Increase celecoxib effect

#	enzyme	Inhibitors	level
0	2C9	amiodarone	Moderate inhibitor
1	2C19	armodafinil	Weak inhibitor
2	2C9	capecitabine	Weak inhibitor
3	2C9	ceritinib	Weak inhibitor
4	2C19	chloramphenicol	In-Vitro Only
5	2C19	cimetidine	Weak inhibitor
6	2C19	citalopram	Weak inhibitor
7	2C9	efavirenz	Weak inhibitor
8	2C19	esomeprazole	Weak inhibitor
9	2C19	felbamate	Weak inhibitor
10	2C9	fenofibrate	In-Vitro Only
11	2C9	fluconazole	Moderate inhibitor
12	2C19	fluconazole	Moderate inhibitor
13	2C19	fluoxetine	Moderate inhibitor
14	2C9	fluvastatin	In-Vitro Only
15	2C9	fluvoxamine	In-Vitro Only
16	2C19	fluvoxamine	Strong inhibitor
17	2C9	isoniazid	Weak inhibitor
18	2C19	isoniazid	Weak inhibitor
19	2C19	ketoconazole	Moderate inhibitor
20	2C19	luliconazole	Weak inhibitor
21	2C9	metronidazole	Moderate inhibitor
22	2C19	modafinil	Weak inhibitor
23	2C19	omeprazole	Weak inhibitor
24	2C19	oral contraceptives	Weak inhibitor
25	2C19	oritavancin	In-Vitro Only
26	2C19	pantoprazole	Weak inhibitor
27	2C9	phenylbutazone	Moderate inhibitor
28	2C9	quercetin	Weak inhibitor
29	2C19	quercetin	In-Vitro Only
30	2C9	sulfamethoxazole	Weak inhibitor
31	2C9	sulfaphenazole	Strong inhibitor
32	2C19	ticlopidine	Strong inhibitor
33	2C19	topiramate	under review
34	2C9	voriconazole	Weak inhibitor
35	2C19	voriconazole	Moderate inhibitor
36	2C9	zafirlukast	Weak inhibitor

The follwing drugs will Increase effect by celecoxib effect

#	enzyme	drug	level
1	2D6	alprenolol	Weak inhibitor
2	2D6	amitriptyline	Weak inhibitor
3	2D6	amphetamine	Weak inhibitor
4	2D6	atomoxetine	Weak inhibitor
5	2D6	brexpiprazole	Weak inhibitor
6	2D6	bufuralol	Weak inhibitor
7	2D6	cariprazine	Weak inhibitor
8	2D6	carvedilol	Weak inhibitor
9	2D6	chlorpheniramine	Weak inhibitor
10	2D6	chlorpromazine	Weak inhibitor
11	2D6	citalopram	Weak inhibitor
12	2D6	clomipramine	Weak inhibitor
13	2D6	clonidine	Weak inhibitor
14	2D6	codeine	Weak inhibitor
15	2D6	debrisoquine	Weak inhibitor
16	2D6	desipramine	Weak inhibitor
17	2D6	deutetrabenazine	Weak inhibitor
18	2D6	dexfenfluramine	Weak inhibitor
19	2D6	dextromethorphan	Weak inhibitor
20	2D6	donepezil	Weak inhibitor
21	2D6	doxepin	Weak inhibitor
22	2D6	eliglustat	Weak inhibitor
23	2D6	encainide	Weak inhibitor
24	2D6	escitalopram	Weak inhibitor
25	2D6	flecainide	Weak inhibitor
26	2D6	fluoxetine	Weak inhibitor
27	2D6	fluvoxamine	Weak inhibitor
28	2D6	ibrutinib	Weak inhibitor
29	2D6	imipramine	Weak inhibitor
30	2D6	lidocaine	Weak inhibitor
31	2D6	metoclopramide	Weak inhibitor
32	2D6	metoprolol	Weak inhibitor
33	2D6	mexiletine	Weak inhibitor
34	2D6	minaprine	Weak inhibitor
35	2D6	nebivolol	Weak inhibitor
36	2D6	nortriptyline	Weak inhibitor
37	2D6	ondansetron	Weak inhibitor
38	2D6	oxycodone	Weak inhibitor
39	2D6	paroxetine	Weak inhibitor
40	2D6	perhexiline	Weak inhibitor
41	2D6	perphenazine	Weak inhibitor
42	2D6	phenacetin	Weak inhibitor
43	2D6	pimavanserin	Weak inhibitor
44	2D6	ponatinib	Weak inhibitor
45	2D6	promethazine	Weak inhibitor
46	2D6	propafenone	Weak inhibitor
47	2D6	propranolol	Weak inhibitor
48	2D6	risperidone	Weak inhibitor
49	2D6	rucaparib	Weak inhibitor
50	2D6	sparteine	Weak inhibitor
51	2D6	tamoxifen	Weak inhibitor
52	2D6	tetrabenzine	Weak inhibitor
53	2D6	thioridazine	Weak inhibitor
54	2D6	timolol	Weak inhibitor
55	2D6	tramadol	Weak inhibitor
56	2D6	umeclidinium	Weak inhibitor
57	2D6	valbenazine	Weak inhibitor
58	2D6	venlafaxine	Weak inhibitor
59	2D6	vilazodone	Weak inhibitor
60	2D6	zuclopenthixol	Weak inhibitor

will decrease celecoxib effect

#

enzyme

inducers

celecoxib will not affect

Strong inhibitor is one that causes a ≥ 5-fold decrease in the plasma AUC values or more than 80% decrease in clearance.
Moderate inhibitor is one that causes a 2 fold to < 5-fold decrease in the plasma AUC values or 50-80% decrease in clearance.
Weak inhibitor is one that causes a ≥ 1.25-fold but < 2-fold decrease in the plasma AUC values or 20-50% decrease in clearance.
In-Vitro Only In-Vitro Only Inhibitor strength.
under review Inhibitor strength level is under review.