DROTRECOGIN ALFA

DROTRECOGIN ALFA

Brand Name & Strength

Xigris® 5mg

Reconstitution

Further Dilution

IV infusion

  • Infusion pump: Dilute to final concentration of 0.1 – 0.2 mg/ml
  • Syringe pump: Dilute to final concentration of 0.1 – 1 mg/ml

    Diluent

    NS

    Administration & Infusion rate

    IV infusion

  • Administer at 24 mcg/kg/hr for a total of 96 hr; stop infusion immediately if bleeding identified
  • The maximum duration of infusion from one preparation step is 12 hr. Multiple infusion periods will be needed to cover entire 96 hr

    Storage & Stability

    RT

    (<25 oC)

    Fridge

    (2 – 8 oC)

    After Reconstitution

    3 hr -

    After dilution

    12 hr 12 hr

    Remarks