about Ipratropium Bromide class, uses, side effects contraindications
Ipratropium Bromide
Short Description
Ipratropium bromide, which was introduced as a bronchodilator in 1975, is used to treat obstructive pulmonary diseases, especially in patients suffering from?chronic bronchitis?.
Ipratropium bromide, a derivative of tropine, inhibits the effect of acetylcholine on the bronchi, which leads to their expansion and facilitates breathing. Ipratropium bromide is given by inhalation only, so no serious side effects are expected in general.
Also, a nasal spray has recently been started to treat?allergic?rhinitis, and it is worth noting that due to the slow effect of ipratropium bromide, it is not recommended to use it when severe asthma attacks occur.
Trade Name & Company Name
effect of Ipratropium Bromide in Pregnancy, Fetal Health
and Breast feeding
Pregnancy
. The published experience with ipratropium during Pregnancy
is limited to case reports. Mild asthma during Pregnancy
is managed with inhaled b2-agonists; therapy for moderate asthma includes inhaled cromolyn, inhaled beclomethasone, and oral theophylline. Severe gestational asthma should be treated with oral corticosteroids at the lowest effective dosage. The pharmacologic management of acute asthma during Pregnancy
includes nebulized b2-agonists, ipratropium, and IV methylprednisolone. Fetal Health
There are no adequate reports or well-controlled studies in human fetuses. It is unknown whether ipratropium crosses the human placenta. Rodent studies are reassuring, revealing no evidence of teratogenicity or IUGR despite the use of doses higher than those used clinically. The highest doses (1000the MRHD) were associated with embryotoxicity. 531 Breastfeeding
There is no published experience in nursing women. It is unknown whether ipratropium enters human breast milk. While lipid-insoluble quaternary bases enter breast milk, it is unlikely ipratropium reaches the neonate to a significant degree since it is not well absorbed systemically after inhalation or oral administration.
the follwing drugs will increse Ipratropium Bromide by inhepiting cyp450
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the follwing drugs will decrease Ipratropium Bromide by inhancing cyp450
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trad drugs based on Ipratropium Bromide
| Gen name | Trade name | Catagory name |
| Ipratropium Bromide | ATROBULM 250MCG-ML SOLUTION FOR INHALATION | |
| Ipratropium Bromide | ATROBULM 500MCG-2ML SOLUTION FOR INHALATION | |
| Ipratropium Bromide | ATROVENT 0.02MG-METERED DOSE INHALER | |
| Ipratropium Bromide | ATROVENT 250MCG-2ML UDV (SOLUTION FOR INHALATION) | |
| Ipratropium Bromide | ATROVENT 500MCG-2ML UDV (SOLUTION FOR INHALATION) | |
other drugs from same cataogory
| Gen name | trade name | catogry |