neostigmine_bromide  - Drug Details
📊 Estimates neostigmine_bromide  Dialyzability By Different_Modalities

neostigmine_bromide 

Complete Drug Information

Drug Name
neostigmine_bromide 
Trade Names
Bloxiverz, Prostigmin, Vagostigmin
Pregnancy Category
AU: B2
Bioavailability
Unclear, probably less than 5%
Routes of Administration
Intramuscular, intravenous, subcutaneous,Oral
Metabolism
Slow hydrolysis by acetylcholinesterase and also by plasma esterases
Elimination
50–90 minutes
Excretion
Unchanged drug (up to 70%) and alcoholic metabolite (30%) are excreted in the urine
Formula
C12H19N2O2+
Molar Mass
223.296
Onset of Action
10-20 min
Duration of Action
up to 4 hrs
Drug Class
Cholinesterase inhibitor
Volume of Distribution
C12H19N2O2+

🤰 Pregnancy Category Information

Category: AU: B2

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.