naloxone  - Drug Details
📊 Estimates naloxone  Dialyzability By Different_Modalities

naloxone 

Complete Drug Information

Drug Name
naloxone 
Trade Names
Narcan
Pregnancy Category
AU: B1 US: C
Bioavailability
2% (by mouth, 90% absorption but high first-pass metabolism)43–54% (intranasal)98% (intramuscular, subcutaneous)
Routes of Administration
Intranasal, intravenous, intramuscular
Metabolism
Liver
Elimination
1–1.5 h
Excretion
Urine, bile
Formula
C19H21NO4
Molar Mass
327.38
Onset of Action
3-7 min
Duration of Action
30–90 min
Drug Class
Opioid antagonist
Volume of Distribution
3 L/kg

🤰 Pregnancy Category Information

Category: AU: B1 US: C

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies have not shown evidence of an increased occurrence of fetal damage.