📊 Estimates hydrocortisone Dialyzability By Different_Modalities

hydrocortisone

Complete Drug Information

Drug Name

hydrocortisone

Trade Names

Cortef

Pregnancy Category

AU: A

Bioavailability

Oral: 96 ± 20%

Routes of Administration

Oral, intravenous, topical, rectal

Protein Binding

92 ± 2% (92–93%)%

Metabolism

11β-HSDsTooltip 11β-Hydroxysteroid dehydrogenases, others

Elimination

1.2–2.0 hours

Excretion

Urine: >90% (<1% unchanged)

Formula

C21H30O5

Molar Mass

362.466

Onset of Action

1.2 ± 0.4 hours

Duration of Action

8–12 hours

Drug Class

Glucocorticoid; Mineralocorticoid

Volume of Distribution

0.4 L/kg

🤰 Pregnancy Category Information

Category: AU: A

Drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus.