📊 Estimates Zoloft Dialyzability By Different_Modalities

Zoloft

Complete Drug Information

Drug Name

Zoloft

Trade Names

Zoloft, Lustral, Setrona

Pregnancy Category

AU: C

Bioavailability

~40–45%

Routes of Administration

Oral

Metabolism

Liver (primarily N-demethylation mainly by CYP2B6; also metabolism by CYP2C19, others)

Elimination

Sertraline: 26 hours (32 hours in females, 22 hours in males; range 13–45 hours) Desmethylsertraline: 62–104 hours

Excretion

Urine (40–45%)Feces (40–45%)

Formula

C17H17Cl2N

Molar Mass

306.23

Drug Class

Selective serotonin reuptake inhibitor (SSRI)

Volume of Distribution

C17H17Cl2N

🤰 Pregnancy Category Information

Category: AU: C

Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible.