Xtandi - Drug Details
๐Ÿ“Š Estimates Xtandi Dialyzability By Different_Modalities

Xtandi

Complete Drug Information

Drug Name
Xtandi
Trade Names
Xtandi
Pregnancy Category
AU: X (High risk)
Bioavailability
Rats: 89.7%Humans: unknown (but at least 84.6% based on recovery from excretion)
Routes of Administration
Oral
Protein Binding
Enzalutamide: 97โ€“98% (primarily to albumin)NDME: 95%%
Metabolism
Liver (primarily CYP2C8 and CYP3A4)
Elimination
Enzalutamide: 5.8 days (range 2.8โ€“10.2 days)NDME: 7.8โ€“8.6 days
Excretion
Urine: 71.0%Bile: 13.6%Feces: 0.39%
Formula
C21H16F4N4O2S
Molar Mass
464.44
Drug Class
Nonsteroidal antiandrogen
Volume of Distribution
C21H16F4N4O2S

๐Ÿคฐ Pregnancy Category Information

Category: AU: X (High risk)

Drugs which have such a high risk of causing permanent damage to the fetus that they should not be used in pregnancy or when there is a possibility of pregnancy.