📊 Estimates venlafaxine Dialyzability By Different_Modalities

venlafaxine

Complete Drug Information

Drug Name

venlafaxine

Trade Names

Effexor

Pregnancy Category

AU: B2

Bioavailability

42±15%

Routes of Administration

Oral

Protein Binding

27±2% (parent compound), 30±12% (active metabolite, desvenlafaxine)%

Metabolism

Extensively metabolised by the liver, primarily via CYP2D6

Elimination

5±2 h (parent compound for immediate release preparations), 15±6 h (parent compound for extended-release preparations), 11±2 h (active metabolite)

Excretion

Kidney (87%; 5% as unchanged drug; 29% as desvenlafaxine and 53% as other metabolites)

Formula

C17H27NO2

Molar Mass

277.408

Drug Class

Serotonin–norepinephrine reuptake inhibitor

Volume of Distribution

7.5 L/kg

🤰 Pregnancy Category Information

Category: AU: B2

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.