📊 Estimates minoxidil Dialyzability By Different_Modalities

minoxidil

Complete Drug Information

Drug Name

minoxidil

Trade Names

Loniten, Rogaine

Pregnancy Category

AU: C

Bioavailability

Oral: ≥90% (absorption)Topical: ~1.2–1.4%

Routes of Administration

Oral, sublingual, topical (solution, foam, spray)

Protein Binding

Minimal or negligible%

Metabolism

Primarily liver via glucuronidation, hydroxylation, and sulfation (SULT1A1, SULT2A1)

Elimination

Oral: 3–4 hoursTopical: 22 hours

Excretion

Urine: >97% (10–15% unchanged; within 12–20 hours for oral and 4 days for topical)

Formula

C9H15N5O

Molar Mass

209.253

Onset of Action

30–60 min

Duration of Action

72 h

Melting Point

248 °C

Drug Class

Potassium channel opener; KATP channel opener

Volume of Distribution

2 L/kg

🤰 Pregnancy Category Information

Category: AU: C

Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible.