📊 Estimates Estrogel Dialyzability By Different_Modalities

Estrogel

Complete Drug Information

Drug Name

Estrogel

Trade Names

Many

Pregnancy Category

AU: B1

Bioavailability

Oral: <5%IM: 100%

Routes of Administration

Oral (tablet)• Sublingual (tablet)• Intranasal (nasal spray)• Transdermal (patch, gel, cream, emulsion, spray)• Vaginal (tablet, cream, suppository, insert, ring)• IM injection (oil solution)• SC injection (aq. soln.Tooltip aqueous solution)• Subcutaneous implant

Protein Binding

~98%:• Albumin: 60%• SHBG: 38%• Free: 2%%

Metabolism

Liver (via hydroxylation, sulfation, glucuronidation)

Elimination

Oral: 13–20 hoursSublingual: 8–18 hoursTransdermal (gel): 37 hoursIM (as EVTooltip estradiol valerate): 4–5 daysIM (as ECTooltip estradiol cypionate): 8–10 daysIVTooltip Intravenous injection (as E2): 1–2 hours

Excretion

Urine: 54%Feces: 6%

Formula

C18H24O2

Molar Mass

272.388

Drug Class

Estrogen

Volume of Distribution

C18H24O2

🤰 Pregnancy Category Information

Category: AU: B1

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies have not shown evidence of an increased occurrence of fetal damage.