loratadine  - Drug Details
📊 Estimates loratadine  Dialyzability By Different_Modalities

loratadine 

Complete Drug Information

Drug Name
loratadine 
Trade Names
Claritin, Claratyne, Clarityn
Pregnancy Category
AU: B1
Bioavailability
almost 100%
Routes of Administration
Oral
Protein Binding
97–99%%
Metabolism
Liver (CYP2D6- and 3A4-mediated)
Elimination
8 hours, active metabolite desloratadine 27 hours
Excretion
40% as conjugated metabolites into urineSimilar amount into the feces
Formula
C22H23ClN2O2
Molar Mass
382.89
Drug Class
Second-generation antihistamine
Volume of Distribution
C22H23ClN2O2

🤰 Pregnancy Category Information

Category: AU: B1

Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus. Animal studies have not shown evidence of an increased occurrence of fetal damage.