Mostly via intracellular kinases; 15-18% is excreted unchanged. Intravenous and subcutaneous bolus injection: 15-18% is excreted unchanged After oral administration, 25% (±21%) of dose is excreted unchanged in urine and 3.8% as a metabolite.
Elimination
Approximately 10 hours after both intravenous infusion and subcutaneous bolus injection ranging from 5.6 to 7.6 hours and 18.4 to 19.7 hours after oral administration, indicative of different elimination phases.
Excretion
Urinary
Formula
C10H12ClN5O3
Molar Mass
285.69
Volume of Distribution
C10H12ClN5O3
🤰 Pregnancy Category Information
Category: AU: D
Drugs which have caused, are suspected to have caused, or may be expected to cause an increased incidence of human fetal malformations or irreversible damage. These drugs may also have adverse pharmacological effects.
